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Highly predictive support vector machine (SVM) models for anthrax toxin lethal factor (LF) inhibitors.

Journal of molecular graphics & modelling 26615468
Anthrax is a highly lethal, acute infectious disease caused by the rod-shaped, Gram-positive bacterium Bacillus anthracis. The anthrax toxin lethal factor (LF), a zinc metalloprotease secreted by the bacilli, plays a key role in anthrax pathogenesis ...
Antidotes Antigens, Bacterial Bacillus anthracis Bacterial Toxins Databases, Chemical High-Throughput Screening Assays Models, Chemical Models, Statistical Predictive Value of Tests Small Molecule Libraries Structure-Activity Relationship Support Vector Machine User-Computer Interface
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