AIMC Topic: Bacterial Toxins
Clear Filters Showing 1 to 8 of 8 articles
Identification of Isomerically Diverse Ginsenosides Using Engineered Aerolysin Nanopore via Non-Translocation Blockade Sensing.
Angewandte Chemie (International ed. in English)
Jun 8, 2025
Typical nanopore sensing depends on slowed translocation through the pore to acquire effective blockade signals. However, this paradigm often suffers from low signal precision and poor resolution, making it challenging to resolve pools of analytes wi...
Identification of novel toxins associated with the extracellular contractile injection system using machine learning.
Molecular systems biology
Jul 28, 2024
Secretion systems play a crucial role in microbe-microbe or host-microbe interactions. Among these systems, the extracellular contractile injection system (eCIS) is a unique bacterial and archaeal extracellular secretion system that injects protein t...
Construction of an aerolysin-based multi-epitope vaccine against an machine learning and artificial intelligence-supported approach.
Frontiers in immunology
Mar 1, 2024
, a gram-negative coccobacillus bacterium, can cause various infections in humans, including septic arthritis, diarrhea (traveler's diarrhea), gastroenteritis, skin and wound infections, meningitis, fulminating septicemia, enterocolitis, peritonitis,...
A smartphone-based system for fluorescence polarization assays.
Biosensors & bioelectronics
Dec 24, 2018
This paper demonstrates the use of a smartphone-based sensor for fluorescence polarization (FP) analysis of biomolecules. The FP detection can rapidly sense ligand-analyte bindings by measuring molecule mobility, and thus, FP-based assays have been w...
Organism burden, toxin concentration, and lactoferrin concentration do not distinguish between clinically significant and nonsignificant diarrhea in patients with Clostridium difficile.
Diagnostic microbiology and infectious disease
Nov 30, 2015
Clostridium difficile infection is often overdiagnosed in patients with mild diarrhea. We evaluated 4 biomarkers as surrogates for clinically significant diarrhea (≥ 3 episodes in 24 hours) in 59 PCR-positive patients with and 59 PCR-positive patient...
Highly predictive support vector machine (SVM) models for anthrax toxin lethal factor (LF) inhibitors.
Journal of molecular graphics & modelling
Nov 17, 2015
Anthrax is a highly lethal, acute infectious disease caused by the rod-shaped, Gram-positive bacterium Bacillus anthracis. The anthrax toxin lethal factor (LF), a zinc metalloprotease secreted by the bacilli, plays a key role in anthrax pathogenesis ...
Development and validation of a hierarchical machine learning method using MALDI-TOF mass spectrometry for rapid SCCmec typing and PVL detection in MRSA: a multi-centre study.
Emerging microbes & infections
Dec 1, 2025
OBJECTIVES: Methicillin-resistant (MRSA) is a major public health concern because of its genotypic diversity and association with severe infections, particularly those caused by strains carrying Panton-Valentine leukocidin (PVL). This study aimed to...
A deep learning method to predict bacterial ADP-ribosyltransferase toxins.
Bioinformatics (Oxford, England)
Jul 1, 2024
MOTIVATION: ADP-ribosylation is a critical modification involved in regulating diverse cellular processes, including chromatin structure regulation, RNA transcription, and cell death. Bacterial ADP-ribosyltransferase toxins (bARTTs) serve as potent v...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31964
- Neural Networks, Computer 30201
- Algorithms 27375
- Deep Learning 26880
- Artificial Intelligence 24818
- Robotics 13382
- Image Processing, Computer-Assisted 9730
- Retrospective Studies 9328
- Magnetic Resonance Imaging 6341
- Reproducibility of Results 5670
- Tomography, X-Ray Computed 4863
- Support Vector Machine 4762
- Computational Biology 4328
- Brain 4125
- Computer Simulation 3932
Recent Journals
- Scientific reports 6689
- Sensors (Basel, Switzerland) 4794
- PloS one 4186
- Neural networks : the official journal of the International Neural Network Society 3026
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1915
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1378
- IEEE journal of biomedical and health informatics 1167
- Journal of chemical information and modeling 1059
- Nature communications 1029
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 872
- Journal of medical Internet research 853
- Briefings in bioinformatics 853