AIMC Topic: Cell-Penetrating Peptides

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SkipCPP-Pred: an improved and promising sequence-based predictor for predicting cell-penetrating peptides.

BMC genomics Oct 16, 2017
BACKGROUND: Cell-penetrating peptides (CPPs) are short peptides (5-30 amino acids) that can enter almost any cell without significant damage. On account of their high delivery efficiency, CPPs are promising candidates for gene therapy and cancer trea...
Computational Biology Internet Amino Acid Sequence Cell-Penetrating Peptides
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PractiCPP: a deep learning approach tailored for extremely imbalanced datasets in cell-penetrating peptide prediction.

Bioinformatics (Oxford, England) Feb 1, 2024
MOTIVATION: Effective drug delivery systems are paramount in enhancing pharmaceutical outcomes, particularly through the use of cell-penetrating peptides (CPPs). These peptides are gaining prominence due to their ability to penetrate eukaryotic cells...
Software Drug Delivery Systems Deep Learning Cell-Penetrating Peptides Eukaryotic Cells
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The Development of Machine Learning Methods in Cell-Penetrating Peptides Identification: A Brief Review.

Current drug metabolism Jan 1, 2019
BACKGROUND: Cell-penetrating Peptides (CPPs) are important short peptides that facilitate cellular intake or uptake of various molecules. CPPs can transport drug molecules through the plasma membrane and send these molecules to different cellular org...
Machine Learning Computational Biology Cell-Penetrating Peptides
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A Novel Amino Acid Sequence-based Computational Approach to Predicting Cell-penetrating Peptides.

Current computer-aided drug design Jan 1, 2019
INTRODUCTION: Machine Learning is a useful tool for the prediction of cell-penetration compounds as drug candidates.
Humans Machine Learning Computer Simulation Computational Biology Structure-Activity Relationship Amino Acid Sequence Cell Membrane Permeability Cell-Penetrating Peptides
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Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.

Methods in molecular biology (Clifton, N.J.) Jan 1, 2015
Cell-penetrating peptides (CPPs) have proven their potential as versatile drug delivery vehicles. Last decade has witnessed an unprecedented growth in CPP-based research, demonstrating the potential of CPPs as therapeutic candidates. In the past, man...
Humans Machine Learning Computer Simulation Animals Computer-Aided Design Support Vector Machine Drug Carriers Proteins Amino Acid Sequence Cell-Penetrating Peptides Molecular Sequence Data Amino Acid Motifs
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