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Coronavirus RNA-Dependent RNA Polymerase

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Interface design of SARS-CoV-2 symmetrical nsp7 dimer and machine learning-guided nsp7 sequence prediction reveals physicochemical properties and hotspots for nsp7 stability, adaptation, and therapeutic design.

Physical chemistry chemical physics : PCCP 38686454
The COVID-19 pandemic, driven by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), necessitates a profound understanding of the virus and its lifecycle. As an RNA virus with high mutation rates, SARS-CoV-2 exhibits genetic variability lea...
Amino Acid Sequence Coronavirus RNA-Dependent RNA Polymerase COVID-19 Humans Machine Learning Mutation Protein Multimerization SARS-CoV-2 Viral Nonstructural Proteins
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