AIMC Topic: Fermentation

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Enhanced Fermentable Sugar Production from Enteromorpha Polysaccharides by the Crude Enzymes of Vibrio sp. H11.

Journal of molecular microbiology and biotechnology
In recent years, large-scale outbreaks of the green alga Enteromorpha prolifera in China's offshore waters have posed a serious threat. This study aimed to improve Enteromorpha polysaccharide (EP) enzymatic sugar production using the hydrolase system...

Optimization of fungi co-fermentation for improving anthraquinone contents and antioxidant activity using artificial neural networks.

Food chemistry
The fermentation products of edible fungi are rich in anthraquinones and have a variety of activities, including the antioxidant activity. Because of the large number of combinations, it is very difficult to obtain the optimal multi-strains co-fermen...

Quantitative analysis of yeast fermentation process using Raman spectroscopy: Comparison of CARS and VCPA for variable selection.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Yeast is one of the most widely used microbial species in the field of microbiology, and it is crucial that rapid and accurate monitoring of its process. Therefore, this study presents a method using Raman spectroscopy for quantitative analysis of ye...

Extraction and optimization of exopolysaccharide from sp. using response surface methodology and artificial neural networks.

Preparative biochemistry & biotechnology
The microbial polysaccharides secreted and produced from various microbes into their extracellular environment is known as exopolysaccharide. These polysaccharides can be secreted from the microbes either in a soluble or insoluble form. sp. is one of...

Accurate and cost-effective prediction of HBsAg titer in industrial scale fermentation process of recombinant Pichia pastoris by using neural network based soft sensor.

Biotechnology and applied biochemistry
In the current work, the attempt was made to apply best-fitted artificial neural network (ANN) architecture and the respective training process for predicting final titer of hepatitis B surface antigen (HBsAg), produced intracellularly by recombinant...

Soft-sensing method based on FDLS-SVM in marine alkaline protease fermentation process.

Preparative biochemistry & biotechnology
To overcome the problem that soft-sensing model cannot be updated with the bioprocess changes, this article proposed a soft-sensing modeling method which combined fuzzy c-means clustering (FCM) algorithm with least squares support vector machine theo...

Estimation of fungal biomass using multiphase artificial neural network based dynamic soft sensor.

Journal of microbiological methods
Interest in low cost cellulase production has become a major challenge in recent years for biorefineries. Fed-batch fermentation of Trichoderma strains for the production of low cost cellulase is carried out on complex media that has various soluble ...

Application of recurrent neural network for online prediction of cell density of recombinant Pichia pastoris producing HBsAg.

Preparative biochemistry & biotechnology
Artificial neural networking (ANN) seems to be a promising soft sensor for implementing current approaches of quality by design (QbD) and process analytical technologies (PAT) in the biopharmaceutical industry. In this study, we aimed to implement be...

Optimization of Cultural Conditions for Cultured in Industrial Wastewater.

BioMed research international
The aim of this study was to optimize the cultural conditions for using industrial wastewater as nature culture through response surface methodology. In our present study, we analyzed the total number of living in the fermentation broth using mult...

Functional expression of porcine interferon-α using a combinational strategy in Pichia pastoris GS115.

Enzyme and microbial technology
Porcine interferon-α (pIFN-α) could be used as the vaccine adjuvant to enhance the antiviral ability of porcine in swine industry. In here, a combinational strategy integrating codon optimization, multiple gene insertion, strong AOX1 promoter, and ef...