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Genes, MHC Class I

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Evaluating NetMHCpan performance on non-European HLA alleles not present in training data.

Frontiers in immunology
Bias in neural network model training datasets has been observed to decrease prediction accuracy for groups underrepresented in training data. Thus, investigating the composition of training datasets used in machine learning models with healthcare ap...

Connecting MHC-I-binding motifs with HLA alleles via deep learning.

Communications biology
The selection of peptides presented by MHC molecules is crucial for antigen discovery. Previously, several predictors have shown impressive performance on binding affinity. However, the decisive MHC residues and their relation to the selection of bin...