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Development of a novel fingerprint for chemical reactions and its application to large-scale reaction classification and similarity.

Journal of chemical information and modeling
Fingerprint methods applied to molecules have proven to be useful for similarity determination and as inputs to machine-learning models. Here, we present the development of a new fingerprint for chemical reactions and validate its usefulness in build...

Quantitative Analysis of Technological Innovation in Knee Arthroplasty: Using Patent and Publication Metrics to Identify Developments and Trends.

The Journal of arthroplasty
BACKGROUND: Surgery is in a constant continuum of innovation with refinement of technique and instrumentation. Arthroplasty surgery potentially represents an area with highly innovative process. This study highlights key area of innovation in knee ar...

Patent Network Analysis and Quadratic Assignment Procedures to Identify the Convergence of Robot Technologies.

PloS one
Because of the remarkable developments in robotics in recent years, technological convergence has been active in this area. We focused on finding patterns of convergence within robot technology using network analysis of patents in both the USPTO and ...

Chemical entity recognition in patents by combining dictionary-based and statistical approaches.

Database : the journal of biological databases and curation
We describe the development of a chemical entity recognition system and its application in the CHEMDNER-patent track of BioCreative 2015. This community challenge includes a Chemical Entity Mention in Patents (CEMP) recognition task and a Chemical Pa...

Chemical named entity recognition in patents by domain knowledge and unsupervised feature learning.

Database : the journal of biological databases and curation
Medicinal chemistry patents contain rich information about chemical compounds. Although much effort has been devoted to extracting chemical entities from scientific literature, limited numbers of patent mining systems are publically available, probab...

Tracing Technological Development Trajectories: A Genetic Knowledge Persistence-Based Main Path Approach.

PloS one
The aim of this paper is to propose a new method to identify main paths in a technological domain using patent citations. Previous approaches for using main path analysis have greatly improved our understanding of actual technological trajectories bu...

What robot for tomorrow and what improvement can we expect?

Current opinion in urology
PURPOSE OF REVIEW: The purpose of this review is to summarize the status of robotic surgery currently, contextualizing the advances and improvements we can expect in the immediate future. Robotics continues to demonstrate increased utility and expans...