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Protein Structural Elements

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A Machine Learning Study on the Thermostability Prediction of (R)--Selective Amine Transaminase from Aspergillus terreus.

BioMed research international
Artificial intelligence technologies such as machine learning have been applied to protein engineering, with unique advantages in protein structure, function prediction, catalytic activity, and other issues in recent years. Screening better mutants i...

Evaluation of Deep Neural Network ProSPr for Accurate Protein Distance Predictions on CASP14 Targets.

International journal of molecular sciences
The field of protein structure prediction has recently been revolutionized through the introduction of deep learning. The current state-of-the-art tool AlphaFold2 can predict highly accurate structures; however, it has a prohibitively long inference ...

PyUUL provides an interface between biological structures and deep learning algorithms.

Nature communications
Structural bioinformatics suffers from the lack of interfaces connecting biological structures and machine learning methods, making the application of modern neural network architectures impractical. This negatively affects the development of structu...