AIMC Topic: Silymarin

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Modelling key ecological factors influencing the distribution and content of silymarin antioxidant in Silybum marianum L.

PloS one
The increasing demand for natural medicine has increased the significance of Silybum marianum as a valuable medicinal plant. It is used to restore liver cells; reduce blood cholesterol; prevent prostate, skin, and breast cancer; and protect cervical ...

Formulation and optimization of silymarin-encapsulated binary micelles for enhanced amyloid disaggregation activity.

Drug development and industrial pharmacy
Silymarin (SLY) is a natural hydrophobic polyphenol that possesses antioxidant and amyloid fibril (Aβ) inhibition activity, but its activity is hindered due to low aqueous solubility. In this study, SLY is encapsulated in binary micelle (SLY-BM) that...