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Silymarin

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Formulation and optimization of silymarin-encapsulated binary micelles for enhanced amyloid disaggregation activity.

Drug development and industrial pharmacy
Silymarin (SLY) is a natural hydrophobic polyphenol that possesses antioxidant and amyloid fibril (Aβ) inhibition activity, but its activity is hindered due to low aqueous solubility. In this study, SLY is encapsulated in binary micelle (SLY-BM) that...