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Type IV Secretion Systems

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Using an optimal set of features with a machine learning-based approach to predict effector proteins for Legionella pneumophila.

PloS one 30682021
Type IV secretion systems exist in a number of bacterial pathogens and are used to secrete effector proteins directly into host cells in order to change their environment making the environment hospitable for the bacteria. In recent years, several ma...
Bacterial Proteins Humans Legionella pneumophila Legionnaires' Disease Models, Genetic Support Vector Machine Type IV Secretion Systems Virulence Factors
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Convolutional neural network-based annotation of bacterial type IV secretion system effectors with enhanced accuracy and reduced false discovery.

Briefings in bioinformatics 31860715
The type IV bacterial secretion system (SS) is reported to be one of the most ubiquitous SSs in nature and can induce serious conditions by secreting type IV SS effectors (T4SEs) into the host cells. Recent studies mainly focus on annotating new T4SE...
Algorithms Neural Networks, Computer Position-Specific Scoring Matrices Type IV Secretion Systems
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