Sensitivity enhancement for pressure sensors over a broad linear range can improve sensing performance for a wide range of applications such as health monitoring and artificial intelligence. Here, inspired by the high-precision mechanosensory mechani... read more
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Aug 20, 2025
The discovery of effective therapeutics remains a complex, costly, and time-consuming endeavor, characterized by high failure rates and significant resource investments. A central bottleneck in early-stage drug discovery is identifying suitable hit c... read more
BackgroundBilling and coding for orthopaedic procedures is a complex process with thousands of procedure codes and associated modifiers in existence. Foot and ankle faces an additional challenge as it is among the highest variability regarding proced... read more
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Aug 20, 2025
Single-cell cis-regulatory relationships (CRRs) are essential for deciphering transcriptional regulation and understanding the pathogenic mechanisms of disease-associated non-coding variants. Existing computational methods struggle to accurately pred... read more
The British journal of psychiatry : the journal of mental science
Aug 20, 2025
Psychotherapy chatbots have attained remarkable fluency, skill and ubiquity - having become the single most frequent reason people use artificial intelligence. Their uncanny ability to engage and validate is a two-edged sword - useful for the majorit... read more
Physical chemistry chemical physics : PCCP
Aug 20, 2025
This study refined the Brown-Ladner (B-L) method and combined it with elemental analysis to construct average molecular structure models of virgin asphalt, aiming to achieve more precise molecular simulations of asphalt materials. The chemical struct... read more
BACKGROUND: Sarcopenia is associated with adverse outcomes in patients with end-stage heart failure. Muscle mass can be quantified via manual segmentation of computed tomography images, but this approach is time-consuming and subject to interobserver... read more
Single-mode biophysical fingerprints have specific overlap when cell heterogeneity is analyzed. The cross-sensitivity between these parameters results in significant fuzzy intervals in cell phenotype classification based on one-dimensional features, ... read more
Small (Weinheim an der Bergstrasse, Germany)
Aug 20, 2025
Chronic and complex wounds pose a major clinical challenge due to the intricate skin architecture and the multifactorial nature of healing. Conventional wound care often fails to restore native skin function and structure. Advances in 3D and 4D biopr... read more
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Aug 20, 2025
Acteoside (ACT) and ferulic acid (FA), the principal bioactive constituents of Baihe Dihuang decoction (BDD), possess established anti-inflammatory and antidepressant properties, but their combined effect on microglial phenotype modulation remains un... read more
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