AIMC Topic: Biosensing Techniques

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Recent progress in multifunctional theranostic hydrogels: the cornerstone of next-generation wound care technologies.

Biomaterials science
Theranostic hydrogels represent a groundbreaking approach by integrating therapeutic and diagnostic capabilities within a single platform, enabling real-time monitoring of wounds and precise treatment applications. These advanced materials are engine...

Urea-mediated growth engineering of Au@Ag core-shell nanostructures: an enzymatic detection strategy with machine learning-assisted comparative analysis.

Mikrochimica acta
A non-invasive, enzyme-based colorimetric biosensor was developed for urea detection in saliva, utilizing a growth-based method with Au@Ag core-shell nanostructures, including CTAB-coated gold nanoparticles (AuNPs) and CTAB-coated gold nanorods with ...

Smart Detection of Food Spoilage Using Microbial Volatile Compounds: Technologies, Challenges, and Future Outlook.

Journal of agricultural and food chemistry
Microbial volatile organic compounds (MVOCs) serve as early, noninvasive indicators of food spoilage and microbial contamination. This review critically assesses current methods for MVOC detection, including gas chromatography-mass spectrometry (GC-M...

Ultrasensitive Detection via Machine Learning-Optimized Bacterial-Imprinted Photoelectrochemical Biosensor with Active/Passive Dual-Mode Validation.

Analytical chemistry
Currently, the existing detection platforms face persistent challenges in achieving reliable bacterial identification within complex matrices, particularly in food and environmental specimens, where matrix interference effects substantially compromis...

Synergizing Nanosensor-Enhanced Wearable Devices with Machine Learning for Precision Health Management Benefiting Older Adult Populations.

ACS nano
Population aging presents significant health challenges and socioeconomic burdens globally, driving an increased demand for precision health management. In the era of big data, the exponential growth of health information is accelerating advances in ...

Modification and applications of glucose oxidase: optimization strategies and high-throughput screening technologies.

World journal of microbiology & biotechnology
Glucose oxidase (GOD), an oxidoreductase (EC 1.1.3.4), catalyzes the oxidation of β-D-glucose to gluconic acid using molecular oxygen as the electron acceptor, with concomitant generation of hydrogen peroxide. Owing to its versatile catalytic propert...

Machine Learning-Assisted Multimodal Early Screening of Lung Cancer Based on a Multiplexed Laser-Induced Graphene Immunosensor.

ACS nano
Lung cancer remains the leading cause of cancer-related mortality worldwide, largely due to late-stage diagnosis. Early detection is critical for improving patient outcomes, yet current screening methods, such as low-dose computed tomography (CT), of...

CRISPR/Cas-Based Biosensing Strategies for Non-Nucleic Acid Contaminants in Food Safety: Status, Challenges, and Perspectives.

Journal of agricultural and food chemistry
Non-nucleic acid targets (non-NATs), such as heavy metals, toxins, and pesticide residues, pose critical threats to food safety. Although CRISPR/Cas systems were initially developed for nucleic acid detection, recent advances have enabled their adapt...

Dual-Mode SERS Lateral Flow Aptamer Assay with Machine Learning-Driven Highly Sensitive Interferon-γ Detection.

ACS synthetic biology
Interferon-γ (IFN-γ), a key pro-inflammatory cytokine, is widely recognized as a critical biomarker for diagnosing and monitoring various immune-related conditions. However, its typically low concentrations in biological fluids─at the picogram-per-mi...

Corona Dynamics of Nanoparticles and Their Functional Design Space in Molecular Sensing.

ACS nano
As nanomaterials increasingly interact with complex biological environments, understanding and designing their interfacial layers is critical for enabling functional and responsive behaviors. The protein corona, a spontaneously formed biomolecular la...