High-throughput screening using automated microscopes is a key driver in
biopharma drug discovery, enabling the parallel evaluation of thousands of drug
candidates for diseases such as cancer. Traditional image analysis and deep
learning approaches... read more
In this uncontrolled, open-label exploratory clinical study, the authors explore the potential of blink data as a digital biomarker for estimating clinical indices of Parkinson's disease (PD) using a machine learning approach. Blink data were collect... read more
BACKGROUND: Gliomas account for approximately 25.5% of all primary brain and central nervous system (CNS) tumors and 80.8% of malignant brain and CNS tumors. The prognosis varies considerably; patients with low-grade gliomas (LGGs) have 5-year surviv... read more
Multilevel selection occurs when short-term individual-level reproductive
interests conflict with longer-term group-level fitness effects. Detecting and
quantifying this phenomenon is key to understanding evolution of traits ranging
from multicellu... read more
Human depth perception from 2D images is systematically distorted, yet the nature of these distortions is not fully understood. By examining error patterns in depth estimation for both humans and deep neural networks (DNNs), which have shown remarkab... read more
Generative Artificial Intelligence (Gen-AI) systems offer significant opportunities for personalized learning in higher education. Studying the effects of personality traits on the use of Gen-AI is crucial for understanding the role of individual dif... read more
The first Biobanking and BioMolecular resources Research Infrastructure-Academy Ethical, Legal, and Social Implications (ELSI)'s Symposium, held in June 2024 at IARC/WHO in Lyon, explored ethical, legal, and societal dimensions of biobanking and biom... read more
Large language models (LLMs) are the engines behind generative Artificial Intelligence (AI) applications, the most well-known being chatbots. As conversational agents, they-much like the humans on whose data they are trained-exhibit social bias. The ... read more
IEEE transactions on pattern analysis and machine intelligence
Aug 19, 2025
This paper proposes the paradigm of large convolutional kernels in designing modern Convolutional Neural Networks (ConvNets). We establish that employing a few large kernels, instead of stacking multiple smaller ones, can be a superior design strateg... read more
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