Progress in biophysics and molecular biology
Dec 17, 2025
Cardiovascular disease (CVD) is a leading cause of mortality worldwide, and the mechanical behavior of arterial wall tissue (AWT) is central to its initiation and progression. This review surveys advances in constitutive models of AWT over the past t... read more
Owing to the inherent complexity and nonlinear variable interactions in biomass gasification, accurate products prediction with limited data poses a significant challenge. Herein, in this study, we proposed a hybrid model framework by mixing thermody... read more
BACKGROUND: Regulated cell death (RCD) is essential for organismal development, as it plays key roles in organ formation, pathogen defense, and the maintenance of homeostasis. However, while RCD subroutines-such as apoptosis, autophagy, pyroptosis, n... read more
Biochimica et biophysica acta. Proteins and proteomics
Dec 17, 2025
Intrinsic disorder in proteins is ubiquitous in nature across various proteomes. The association of intrinsically disordered proteins (IDP) with a large variety of biomolecules is essential in many cellular functions. Moreover, IDPs are involved in m... read more
Neuroscience and biobehavioral reviews
Dec 17, 2025
The rapid advances in the capabilities of Large Language Models (LLMs) have galvanised public and scientific debates over whether artificial systems might one day be conscious. Prevailing optimism is often grounded in computational functionalism: the... read more
Journal of the American Academy of Dermatology
Dec 17, 2025
BACKGROUND: Precise histopathologic diagnosis of melanocytic neoplasms is required to guide appropriate clinical management; however, significant interobserver variability remains a challenge and may lead to suboptimal management. OBJECTIVE: To quant... read more
Prostate cancer (PCa) remains the second leading cause of cancer-related mortality among U.S. men, driven in large part by metastatic castration-resistant prostate cancer (mCRPC) despite initial responses to androgen-receptor (AR)-targeted therapies.... read more
Gene expression regulatory elements (GEREs) play a pivotal role in the control of gene transcription and translation. The design of GEREs with precise and tunable activity remains a major challenge in synthetic biology. Over the past decades, enginee... read more
BACKGROUND: Modern supercritical fluid chromatography (SFC) enables fast and efficient separations owing to the low viscosity and high diffusivity of supercritical mobile phases. However, its retention mechanisms remain incompletely understood, limit... read more
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