Application of artificial intelligence-based magnetic resonance imaging in diagnosis of cerebral small vessel disease.

Journal: CNS neuroscience & therapeutics
PMID:

Abstract

Cerebral small vessel disease (CSVD) is an important cause of stroke, cognitive impairment, and other diseases, and its early quantitative evaluation can significantly improve patient prognosis. Magnetic resonance imaging (MRI) is an important method to evaluate the occurrence, development, and severity of CSVD. However, the diagnostic process lacks quantitative evaluation criteria and is limited by experience, which may easily lead to missed diagnoses and misdiagnoses. With the development of artificial intelligence technology based on deep learning, the extraction of high-dimensional features in imaging can assist doctors in clinical decision-making, and it has been widely used in brain function and mental disorders, and cardiovascular and cerebrovascular diseases. This paper summarizes the global research results in recent years and briefly describes the application of deep learning in evaluating CSVD signs in MRI imaging, including recent small subcortical infarcts, lacunes of presumed vascular origin, vascular white matter hyperintensity, enlarged perivascular spaces, cerebral microbleeds, brain atrophy, cortical superficial siderosis, and cortical cerebral microinfarct.

Authors

  • Xiaofei Hu
    Department of Radiology, Southwest Hospital, Third Military Medical University (Army Military Medical University), Chongqing, China.
  • Li Liu
    Metanotitia Inc., Shenzhen, China.
  • Ming Xiong
    Department of Digital Medicine, School of Biomedical Engineering and Medical Imaging, Third Military Medical University (Army Medical University), Chongqing, China.
  • Jie Lu
    Department of Endocrinology and Metabolism, the Affiliated Hospital of Qingdao University, Qingdao, People's Republic of China.