BACKGROUND: The impact of high body mass index (BMI) states and associated proteomic factors on brain ageing and Alzheimer's disease (AD) remains unclear.
BACKGROUND: Alzheimer's disease (AD) might impact the complexity of cerebral cortex, and the underlying biological mechanisms responsible for cortical changes in the AD cortex remain unclear.
BACKGROUNDS: Gastric cancer (GC) is a prevalent malignancy affecting the digestive system. We aimed to develop a risk prediction model based on endoscopic atrophy classification for GC.
Comorbid cardiovascular and metabolic risk factors (CVM) differentially impact brain structure and increase dementia risk, but their specific magnetic resonance imaging signatures (MRI) remain poorly characterized. To address this, we developed and v...
BACKGROUND: Chronic kidney disease (CKD) is a global health concern characterised by irreversible renal damage that is often assessed using invasive renal biopsy. Accurate evaluation of interstitial fibrosis and tubular atrophy (IFTA) is crucial for ...
OBJECTIVE: Accurate personalized survival prediction in amyotrophic lateral sclerosis is essential for effective patient care planning. This study investigates whether grey and white matter changes measured by magnetic resonance imaging can improve i...
BACKGROUND: Single-subject voxel-based morphometry (VBM) is a powerful technique for reader-independent detection of brain atrophy in structural magnetic resonance imaging (MRI) to support the (differential) diagnosis and staging of neurodegenerative...
Primary lateral sclerosis (PLS) is a motor neuron disease (MND) which mainly affects upper motor neurons. Within the MND spectrum, PLS is much more slowly progressive than amyotrophic laterals sclerosis (ALS). `Classical` ALS is characterized by cata...
BACKGROUND: Alzheimer's Disease is a neurodegenerative condition leading to irreversible and progressive brain damage, with possible features such as structural atrophy. Effective precision diagnosis is crucial for slowing disease progression and red...
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