BACKGROUND: Severe tubular atrophy/interstitial fibrosis are critical pathological features associated with poor prognosis in IgA nephropathy (IgAN). The early identification of patients at high risk for severe tubular damage could guide clinical man...
BACKGROUND: Structural brain deficits associated with generalized anxiety disorder (GAD), panic disorder (PD), and obsessive-compulsive disorder (OCD) have been documented, but their integration within a unified framework remains unexplored. This stu...
BACKGROUND: This study aims to apply a semi-supervised machine learning approach for classifying major depressive disorder (MDD) patients into more homogeneous cognitive subtypes based on multidimensional cognitive profiles, and to perform multimodal...
AIM: The aim of this study was to develop and validate a deep learning-based automatic classification algorithm for the medial temporal lobe atrophy (MTA) score in patients with cognitive impairment.
BACKGROUND: The impact of high body mass index (BMI) states and associated proteomic factors on brain ageing and Alzheimer's disease (AD) remains unclear.
Magnetic resonance Imaging (MRI)-derived brain-age prediction is a promising biomarker of biological brain aging. Accelerated brain aging has been found in Alzheimer's disease (AD) and other neurodegenerative diseases. However, no previous studies ha...
BACKGROUND: Alzheimer's disease (AD) might impact the complexity of cerebral cortex, and the underlying biological mechanisms responsible for cortical changes in the AD cortex remain unclear.
BACKGROUNDS: Gastric cancer (GC) is a prevalent malignancy affecting the digestive system. We aimed to develop a risk prediction model based on endoscopic atrophy classification for GC.
Comorbid cardiovascular and metabolic risk factors (CVM) differentially impact brain structure and increase dementia risk, but their specific magnetic resonance imaging signatures (MRI) remain poorly characterized. To address this, we developed and v...
BACKGROUND: Chronic kidney disease (CKD) is a global health concern characterised by irreversible renal damage that is often assessed using invasive renal biopsy. Accurate evaluation of interstitial fibrosis and tubular atrophy (IFTA) is crucial for ...
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