AIMC Topic: Atrophy

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The impact of Alzheimer's disease on cortical complexity and its underlying biological mechanisms.

Brain research bulletin
BACKGROUND: Alzheimer's disease (AD) might impact the complexity of cerebral cortex, and the underlying biological mechanisms responsible for cortical changes in the AD cortex remain unclear.

A risk prediction model for gastric cancer based on endoscopic atrophy classification.

BMC cancer
BACKGROUNDS: Gastric cancer (GC) is a prevalent malignancy affecting the digestive system. We aimed to develop a risk prediction model based on endoscopic atrophy classification for GC.

Machine learning reveals distinct neuroanatomical signatures of cardiovascular and metabolic diseases in cognitively unimpaired individuals.

Nature communications
Comorbid cardiovascular and metabolic risk factors (CVM) differentially impact brain structure and increase dementia risk, but their specific magnetic resonance imaging signatures (MRI) remain poorly characterized. To address this, we developed and v...

Artificial intelligence for predicting interstitial fibrosis and tubular atrophy using diagnostic ultrasound imaging and biomarkers.

BMJ health & care informatics
BACKGROUND: Chronic kidney disease (CKD) is a global health concern characterised by irreversible renal damage that is often assessed using invasive renal biopsy. Accurate evaluation of interstitial fibrosis and tubular atrophy (IFTA) is crucial for ...

Regional Cerebral Atrophy Contributes to Personalized Survival Prediction in Amyotrophic Lateral Sclerosis: A Multicentre, Machine Learning, Deformation-Based Morphometry Study.

Annals of neurology
OBJECTIVE: Accurate personalized survival prediction in amyotrophic lateral sclerosis is essential for effective patient care planning. This study investigates whether grey and white matter changes measured by magnetic resonance imaging can improve i...

Clinical validation of artificial intelligence-based single-subject morphometry without normative reference database.

Journal of Alzheimer's disease : JAD
BACKGROUND: Single-subject voxel-based morphometry (VBM) is a powerful technique for reader-independent detection of brain atrophy in structural magnetic resonance imaging (MRI) to support the (differential) diagnosis and staging of neurodegenerative...

Hypothalamic atrophy in primary lateral sclerosis, assessed by convolutional neural network-based automatic segmentation.

Scientific reports
Primary lateral sclerosis (PLS) is a motor neuron disease (MND) which mainly affects upper motor neurons. Within the MND spectrum, PLS is much more slowly progressive than amyotrophic laterals sclerosis (ALS). `Classical` ALS is characterized by cata...

MHAGuideNet: a 3D pre-trained guidance model for Alzheimer's Disease diagnosis using 2D multi-planar sMRI images.

BMC medical imaging
BACKGROUND: Alzheimer's Disease is a neurodegenerative condition leading to irreversible and progressive brain damage, with possible features such as structural atrophy. Effective precision diagnosis is crucial for slowing disease progression and red...