AIMC Topic: Cerebral Small Vessel Diseases
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A multimodal MRI-based machine learning framework for classifying cognitive impairment in cerebral small vessel disease.
Scientific reports
Apr 16, 2025
The heterogeneity of cerebral small vessel disease (CSVD) with mild cognitive impairment (MCI) presents a challenge for diagnosis and classification. This study aims to propose a multimodal magnetic resonance imaging (MRI)-based machine learning fram...
Deep learning assisted retinal microvasculature assessment and cerebral small vessel disease in Fabry disease.
Orphanet journal of rare diseases
Apr 3, 2025
PURPOSE: The aim of this study was to assess retinal microvascular parameters (RMPs) in Fabry disease (FD) using deep learning, and analyze the correlation with brain lesions related to cerebral small vessel disease (CSVD).
Development and validation of radiomics and deep transfer learning models to assess cognitive impairment in patients with cerebral small vessel disease.
Neuroscience
Mar 9, 2025
Cognitive impairment in cerebral small vessel disease (CSVD) progresses subtly but carries significant clinical consequences, necessitating effective diagnostic tools. This study developed and validated predictive models for CSVD-related cognitive im...
SHIVA-CMB: a deep-learning-based robust cerebral microbleed segmentation tool trained on multi-source T2*GRE- and susceptibility-weighted MRI.
Scientific reports
Dec 28, 2024
Cerebral microbleeds (CMB) represent a feature of cerebral small vessel disease (cSVD), a prominent vascular contributor to age-related cognitive decline, dementia, and stroke. They are visible as spherical hypointense signals on T2*- or susceptibili...
Artificial intelligence-assisted oculo-gait measurements for cognitive impairment in cerebral small vessel disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Oct 16, 2024
INTRODUCTION: Oculomotor and gait dysfunctions are closely associated with cognition. However, oculo-gait patterns and their correlation with cognition in cerebral small vessel disease (CSVD) remain unclear.
Deep learning-based segmentation in MRI-(immuno)histological examination of myelin and axonal damage in normal-appearing white matter and white matter hyperintensities.
Brain pathology (Zurich, Switzerland)
Aug 23, 2024
The major vascular cause of dementia is cerebral small vessel disease (SVD). Its diagnosis relies on imaging hallmarks, such as white matter hyperintensities (WMH). WMH present a heterogenous pathology, including myelin and axonal loss. Yet, these mi...
Establishment and validation of a risk stratification model for stroke risk within three years in patients with cerebral small vessel disease using a combined MRI and machine learning algorithm.
SLAS technology
Aug 21, 2024
BACKGROUND: Cerebral small vessel disease (CSVD) is a major cause of stroke, particularly in the elderly population, leading to significant morbidity and mortality. Accurate identification of high-risk patients and timing of stroke occurrence plays a...
Improved Dementia Prediction in Cerebral Small Vessel Disease Using Deep Learning-Derived Diffusion Scalar Maps From T1.
Stroke
Aug 15, 2024
BACKGROUND: Cerebral small vessel disease is the most common pathology underlying vascular dementia. In small vessel disease, diffusion tensor imaging is more sensitive to white matter damage and better predicts dementia risk than conventional magnet...
Development and validation of radiology-clinical statistical and machine learning model for stroke-associated pneumonia after first intracerebral haemorrhage.
BMC pulmonary medicine
Jul 24, 2024
BACKGROUND: Society is burdened with stroke-associated pneumonia (SAP) after intracerebral haemorrhage (ICH). Cerebral small vessel disease (CSVD) complicates clinical manifestations of stroke. In this study, we redefined the CSVD burden score and in...
Improving the classification of multiple sclerosis and cerebral small vessel disease with interpretable transfer attention neural network.
Computers in biology and medicine
May 1, 2024
As an autoimmune-mediated inflammatory demyelinating disease of the central nervous system, multiple sclerosis (MS) is often confused with cerebral small vessel disease (cSVD), which is a regional pathological change in brain tissue with unknown path...
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