High soluble CD30 levels and associated anti-HLA antibodies in patients with failed renal allografts.

Journal: The International journal of artificial organs
PMID: 28058698

Abstract

INTRODUCTION: Serum soluble CD30 (sCD30), a 120-kD glycoprotein that belongs to the tumor necrosis factor receptor family, has been suggested as a marker of rejection in kidney transplant patients. The aim of this study was to evaluate the relationship between sCD30 levels and anti-HLA antibodies, and to compare sCD30 levels in patients undergoing hemodialysis (HD) with and without failed renal allografts and transplant recipients with functioning grafts.

Authors

  • Gonca E Karahan
    Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul University, Istanbul - Turkey.
  • Yasar Caliskan
    Division of Nephrology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul - Turkey.
  • Kursat Ozdilli
    Pediatric Bone Marrow Transplantation Unit, Medipol University, Istanbul - Turkey.
  • Cigdem Kekik
    Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul University, Istanbul - Turkey.
  • Huseyin Bakkaloglu
    Division of Transplant Surgery, Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul - Turkey.
  • Bahar Caliskan
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Istanbul Faculty of Medicine, Istanbul University, Istanbul - Turkey.
  • Aydin Turkmen
    Pediatric Bone Marrow Transplantation Unit, Medipol University, Istanbul - Turkey.
  • Mehmet S Sever
    Pediatric Bone Marrow Transplantation Unit, Medipol University, Istanbul - Turkey.
  • Fatma S Oguz
    Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul University, Istanbul - Turkey.

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