Beyond the Conventional Structural MRI: Clinical Application of Deep Learning Image Reconstruction and Synthetic MRI of the Brain.

Journal: Investigative radiology
PMID:

Abstract

Recent technological advancements have revolutionized routine brain magnetic resonance imaging (MRI) sequences, offering enhanced diagnostic capabilities in intracranial disease evaluation. This review explores 2 pivotal breakthrough areas: deep learning reconstruction (DLR) and quantitative MRI techniques beyond conventional structural imaging. DLR using deep neural networks facilitates accelerated imaging with improved signal-to-noise ratio and spatial resolution, enhancing image quality with short scan times. DLR focuses on supervised learning applied to clinical implementation and applications. Quantitative MRI techniques, exemplified by 2D multidynamic multiecho, 3D quantification using interleaved Look-Locker acquisition sequences with T2 preparation pulses, and magnetic resonance fingerprinting, enable precise calculation of brain-tissue parameters and further advance diagnostic accuracy and efficiency. Potential DLR instabilities and quantification and bias limitations will be discussed. This review underscores the synergistic potential of DLR and quantitative MRI, offering prospects for improved brain imaging beyond conventional methods.

Authors

  • Yangsean Choi
    Department of Radiology, Seoul Saint Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • Ji Su Ko
  • Ji Eun Park
    Department of Anatomy and Cell Biology, College of Medicine, Dong-A University, Busan 602-714, Korea.
  • Geunu Jeong
  • Minkook Seo
    Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, 06591, Republic of Korea.
  • Yohan Jun
    School of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea.
  • Shohei Fujita
    Department of Radiology, Juntendo University School of Medicine.
  • Berkin Bilgic
    Department of Radiology, Harvard Medical School, Boston, MA, USA.