Genetic Analysis of Potential Biomarkers and Therapeutic Targets in Ferroptosis from Steroid-Induced Osteonecrosis of the Femoral Head Based on Machine Learning.

Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
PMID:

Abstract

OBJECTIVE: To locate the candidate therapeutic target genes involved in ferroptosis in steroid-induced osteonecrosis of the femoral head (SONFH).

Authors

  • Jun Zhao
  • Junjie Guan
    Department of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
  • Xingshi Zhang
    Department of Orthopaedic Surgery, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Guangdong, China.
  • Jizhao Jiang
    Department of Orthopaedic Surgery, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Guangdong, China.
  • Kun Dou
    Department of Orthopaedic Surgery, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Guangdong, China.