AIMC Topic: Suppressor of Cytokine Signaling 1 Protein

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Integrated bulk and single-cell transcriptomics identify RELB, S100A9, and SOCS1 as key autophagy-endoplasmic reticulum stress genes linking T2DM with MAFLD.

Scientific reports Oct 29, 2025
Type 2 diabetes mellitus (T2DM) and metabolism-associated fatty liver disease (MAFLD) are prevalent metabolic disorders with shared pathophysiological mechanisms. A comprehensive understanding of the molecular pathways involved in their onset and pro...
Humans Animals Male Gene Expression Profiling Transcriptome Diabetes Mellitus, Type 2 Single-Cell Analysis Protein Interaction Maps Gene Regulatory Networks Rats Autophagy Non-alcoholic Fatty Liver Disease Endoplasmic Reticulum Stress Suppressor of Cytokine Signaling 1 Protein Transcription Factor RelB
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Significant correlation between ferroptosis-associated genes and ulcerative colitis: implications for diagnosis and treatment.

European journal of medical research Aug 29, 2025
BACKGROUND: Ulcerative colitis (UC) is a significant type of inflammatory bowel disease (IBD). Ferroptosis is a type of procedural death that is associated with different types of diseases to various degrees. This study aimed to explore the key ferro...
Humans Animals Mice Disease Models, Animal Ferroptosis Colitis, Ulcerative Tissue Inhibitor of Metalloproteinase-1 Dextran Sulfate Suppressor of Cytokine Signaling 1 Protein
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Genetic Analysis of Potential Biomarkers and Therapeutic Targets in Ferroptosis from Steroid-Induced Osteonecrosis of the Femoral Head Based on Machine Learning.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP Aug 1, 2024
OBJECTIVE: To locate the candidate therapeutic target genes involved in ferroptosis in steroid-induced osteonecrosis of the femoral head (SONFH).
Humans Machine Learning Biomarkers Steroids Computational Biology Ferroptosis Femur Head Necrosis Suppressor of Cytokine Signaling 1 Protein Proto-Oncogene Mas
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New Computational Tool Based on Machine-learning Algorithms for the Identification of Rhinovirus Infection-Related Genes.

Combinatorial chemistry & high throughput screening Jan 1, 2019
BACKGROUND: Human rhinovirus has different identified serotypes and is the most common cause of cold in humans. To date, many genes have been discovered to be related to rhinovirus infection. However, the pathogenic mechanism of rhinovirus is difficu...
Humans Picornaviridae Infections Gene Expression Profiling Computational Biology Membrane Proteins Support Vector Machine Suppressor of Cytokine Signaling 1 Protein
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