Bimodal machine learning model for unstable hips in infants: integration of radiographic images with automatically-generated clinical measurements.

Journal: Scientific reports
Published Date:

Abstract

Bimodal convolutional neural networks (CNNs) are frequently combined with patient information or several medical images to enhance the diagnostic performance. However, the technologies that integrate automatically generated clinical measurements within the images are scarce. Hence, we developed a bimodal model that produced automatic algorithm for clinical measurement (aaCM) from radiographic images and integrated the model with CNNs. In this multicenter research project, the diagnostic performance of the model was investigated with 813 radiographic hip images of infants at risk of developmental dysplasia of the hips (232 and 581 images of unstable and stable hips, respectively), with the ground truth defined by provocative examinations. The results indicated that the accuracy of aaCM was equal or higher than that of specialists, and the bimodal model showed better diagnostic performance than LightGBM, XGBoost, SVM, and single CNN models. aaCM can provide expert's knowledge in a high level, and our proposed bimodal model has better performance than the state-of-art models.

Authors

  • Hirokazu Shimizu
    Department of Radiology, Saitama Medical University, 38 Morohongou, Moroyama-machi, Iruma-gun, Saitama, Japan.
  • Ken Enda
    Department of Cancer Pathology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
  • Hidenori Koyano
    Graduate School of Biomedical Science and Engineering, Hokkaido University, Sapporo, Hokkaido, Japan.
  • Tomohiro Shimizu
    Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N15W7, Sapporo, Hokkaido 060-8638, Japan.
  • Shun Shimodan
    Department of Orthopaedic Surgery, Kushiro City General Hospital, Kushiro, Hokkaido, Japan.
  • Komei Sato
    Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
  • Takuya Ogawa
    Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
  • Shinya Tanaka
    Department of Cancer Pathology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
  • Norimasa Iwasaki
    Department of Orthopedic Surgery, Hokkaido University Hospital, Nishi 5 Chome Kita 14 Jo, Kita Ward, Sapporo, Hokkaido 060-8648, Japan.
  • Daisuke Takahashi
    HACARUS INC., Kyoto, Japan.