New GO-based measures in multiple network alignment.

Journal: Bioinformatics (Oxford, England)
PMID:

Abstract

MOTIVATION: Protein-protein interaction (PPI) networks provide valuable insights into the function of biological systems. Aligning multiple PPI networks may expose relationships beyond those observable by pairwise comparisons. However, assessing the biological quality of multiple network alignments is a challenging problem.

Authors

  • Kimia Yazdani
    Department of Computer Science, University of California, Irvine, CA 92697-3435, United States.
  • Reza Mousapour
    Department of Computer Engineering, Sharif University of Technology, Tehran 1458889694, Iran.
  • Wayne B Hayes
    Department of Computer Science, University of California, Irvine, CA 92697-3435, USA.