Optimizing graph neural network architectures for schizophrenia spectrum disorder prediction using evolutionary algorithms.

Journal: Computer methods and programs in biomedicine
Published Date:

Abstract

BACKGROUND AND OBJECTIVE: The accurate diagnosis of schizophrenia spectrum disorder plays an important role in improving patient outcomes, enabling timely interventions, and optimizing treatment plans. Functional connectivity analysis, utilizing functional magnetic resonance imaging data, has been demonstrated to offer invaluable biomarkers conducive to clinical diagnosis. However, previous studies mainly focus on traditional machine learning methods or hand-crafted neural networks, which may not fully capture the spatial topological relationship between brain regions.

Authors

  • Shurun Wang
  • Hao Tang
    Department of Urology, Eastern Theater General Hospital of Chinese People's Liberation Army, Nanjing, Jiangsu 210000, China.
  • Ryutaro Himeno
    Graduate School of Medicine, Juntendo University, Tokyo, 1138421, Japan.
  • Jordi Solé-Casals
    Data and Signal Processing Group, University of Vic-Central University of Catalonia, 08500 Vic, Catalonia, Spain.
  • Cesar F Caiafa
    Instituto Argentino de Radioastronomía-CCT La Plata, CONICET/CIC-PBA/UNLP, V. Elisa 1894, Argentina.
  • Shuning Han
    Data and Signal Processing Research Group, University of Vic-Central University of Catalonia, Vic, 08500, Spain; Image Processing Research Group, RIKEN Center for Advanced Photonics, RIKEN, Wako-Shi, Saitama, 351-0198, Japan.
  • Shigeki Aoki
  • Zhe Sun
    Centre for Atmospheric Science, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK.