Physiological control for left ventricular assist devices based on deep reinforcement learning.

Journal: Artificial organs
PMID:

Abstract

BACKGROUND: The improvement of controllers of left ventricular assist device (LVAD) technology supporting heart failure (HF) patients has enormous impact, given the high prevalence and mortality of HF in the population. The use of reinforcement learning for control applications in LVAD remains minimally explored. This work introduces a preload-based deep reinforcement learning control for LVAD based on the proximal policy optimization algorithm.

Authors

  • Diego Fernández-Zapico
  • Thijs Peirelinck
    Department of Electrical Engineering (ESAT), KU Leuven, Leuven, Belgium.
  • Geert Deconinck
    Department of Electrical Engineering (ESAT), KU Leuven, Leuven, Belgium.
  • Dirk W Donker
    Cardiovascular and Respiratory Physiology, University of Twente, Enschede, the Netherlands.
  • Libera Fresiello
    Cardiovascular and Respiratory Physiology, University of Twente, Enschede, the Netherlands.