Prediction of gestational diabetes mellitus by multiple biomarkers at early gestation.

Journal: BMC pregnancy and childbirth
PMID: 39285345

Abstract

BACKGROUND: It remains unclear which early gestational biomarkers can be used in predicting later development of gestational diabetes mellitus (GDM). We sought to identify the optimal combination of early gestational biomarkers in predicting GDM in machine learning (ML) models.

Authors

  • Meng-Nan Yang
    Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Department of Pediatrics, Xinhua Hospital, Early Life Health Institute, Shanghai Jiao-Tong University School of Medicine, Kong-Jiang Road, Shanghai, 200092, China.
  • Lin Zhang
    Laboratory of Molecular Translational Medicine, Centre for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Clinical Research Center for Birth Defects of Sichuan Province, West China Second Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. Electronic address: zhanglin@scu.edu.cn.
  • Wen-Juan Wang
    Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Department of Pediatrics, Xinhua Hospital, Early Life Health Institute, Shanghai Jiao-Tong University School of Medicine, Kong-Jiang Road, Shanghai, 200092, China.
  • Rong Huang
    School of Nursing, Chuanbei Medical College, Nanchong, China.
  • Hua He
    State Key Laboratory of Heavy Oil Processing and College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao 266580, China.
  • Tao Zheng
    Guangzhou Institute of Energy Conversion, Chinese Academy of Sciences, Guangzhou 510640, People's Republic of China; Key Laboratory of Renewable Energy, Chinese Academy of Sciences, Guangzhou 510640, People's Republic of China. Electronic address: zhengtao@ms.giec.ac.cn.
  • Guang-Hui Zhang
    Department of Clinical Assay Laboratory, Xinhua Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200092, China.
  • Fang Fang
    Department of Cardiology, Central War Zone General Hospital of the Chinese People's Liberation Army, Wuhan 430061, China.
  • Justin Cheng
    Prosserman Centre for Population Health Research, Department of Obstetrics and Gynecology, Mount Sinai Hospital, Faculty of Medicine, Lunenfeld-Tanenbaum Research Institute, University of Toronto, L5-240, Murray Street 60, Toronto, ON, M5T 3H7, Canada.
  • Fei Li
    Institute for Precision Medicine, Tsinghua University, Beijing, China.
  • Fengxiu Ouyang
    MOE-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Jiong Li
    Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Department of Pediatrics, Xinhua Hospital, Early Life Health Institute, Shanghai Jiao-Tong University School of Medicine, Kong-Jiang Road, Shanghai, 200092, China.
  • Jun Zhang
    First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.
  • Zhong-Cheng Luo
    Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Department of Pediatrics, Xinhua Hospital, Early Life Health Institute, Shanghai Jiao-Tong University School of Medicine, Kong-Jiang Road, Shanghai, 200092, China. zc.luo@utoronnto.ca.

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