AIMC Topic: Insulin-Like Growth Factor I
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Interpreting IGF-1 in children treated with recombinant growth hormone: challenges during early puberty.
Frontiers in endocrinology
Jan 21, 2025
OBJECTIVE: It can be challenging to determine the correct dosage of recombinant growth hormone (GH) in children with GH deficiency, leading to highly variable treatment responses. Insulin-like growth factor-1 (IGF-1) is a tool for monitoring GH treat...
Prediction of gestational diabetes mellitus by multiple biomarkers at early gestation.
BMC pregnancy and childbirth
Sep 16, 2024
BACKGROUND: It remains unclear which early gestational biomarkers can be used in predicting later development of gestational diabetes mellitus (GDM). We sought to identify the optimal combination of early gestational biomarkers in predicting GDM in m...
Adult
Case-Control Studies
China
Fibronectins
Humans
Insulin-Like Growth Factor I
Blood Glucose
Diabetes, Gestational
Logistic Models
ROC Curve
Adiponectin
Predictive Value of Tests
Machine Learning
Sex Hormone-Binding Globulin
C-Reactive Protein
Insulin-Like Growth Factor Binding Protein 2
Biomarkers
Pregnancy Trimester, First
Pregnancy
Female
Application of a Machine Learning Technology in the Definition of Metabolically Healthy and Unhealthy Status: A Retrospective Study of 2567 Subjects Suffering from Obesity with or without Metabolic Syndrome.
Nutrients
Jan 15, 2022
The key factors playing a role in the pathogenesis of metabolic alterations observed in many patients with obesity have not been fully characterized. Their identification is crucial, and it would represent a fundamental step towards better management...
Humans
Artificial Intelligence
Machine Learning
Health Status
Metabolic Syndrome
Risk Factors
Obesity
Glycated Hemoglobin
Biomarkers
Adult
Adipose Tissue
Alanine Transaminase
Prognosis
Male
Absorptiometry, Photon
Retrospective Studies
Middle Aged
Obesity, Metabolically Benign
Female
Insulin-Like Growth Factor I
Metabolic profile of children with extrahepatic portal vein obstruction undergoing meso-Rex bypass.
The Journal of surgical research
Dec 22, 2017
BACKGROUND: Extrahepatic portal vein obstruction (EHPVO) in children is often associated with growth restriction, which improves after the restoration of portal venous flow with a meso-Rex bypass, but the physiologic mechanism is unknown. The purpose...
Caloric restriction and IGF-I administration promote rabbit fecundity: Possible interrelationships and mechanisms of action.
Theriogenology
Dec 18, 2016
The aim of these in vivo and in vitro studies was to examine the influence of caloric restriction (CR), and the administration of insulin-like growth factor (IGF-I), on rabbit fecundity and to understand the interrelationships between CR and IGF-I, a...
Influence of post-insemination nutrition on embryonic development in beef heifers.
Theriogenology
Nov 24, 2016
Previous studies have demonstrated that a decrease in nutrition immediately following AI reduces pregnancy success in beef heifers. The objective of this experiment was to determine if nutrient restriction following AI impacted early embryonic develo...
Lower prevalence of proliferative diabetic retinopathy in elderly onset patients with diabetes.
Diabetes research and clinical practice
Sep 21, 2016
AIMS: To assess diabetic retinopathy (DR) prevalence between elderly onset and younger onset diabetes with similar diabetes duration and evaluate the association between DR prevalence and serum insulin-like growth factor 1 (IGF-1) levels.
Plasma insulin-like growth factor-II (IGF-II) and IGF-II/IGF-I ratio in a chilean case of Doege-Potter Syndrome.
Revista medica de Chile
Oct 1, 2023
INTRODUCTION: Doege-Potter syndrome is a rare clinical entity characterized by recurrent hypoglycemic events caused by non-pancreatic tumors secreting an incompletely processed high-molecular-weight form of Insulin-like Growth factor-II (IGF-II).
IGF-1 stabilizes goat sperm mitochondrial transmembrane potential and reduces dna fragmentation.
Cryo letters
Jan 1, 2023
BACKGROUND: Antioxidant present in sperm cells protects them from oxidative damage. However, sperm are more susceptible to peroxidative damages due to the loss of these enzymes during cryopreservation and their survival and fertility may be compromis...
Machine Learning-based Prediction Model for Treatment of Acromegaly With First-generation Somatostatin Receptor Ligands.
The Journal of clinical endocrinology and metabolism
Jun 16, 2021
CONTEXT: Artificial intelligence (AI), in particular machine learning (ML), may be used to deeply analyze biomarkers of response to first-generation somatostatin receptor ligands (fg-SRLs) in the treatment of acromegaly.
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