Bile acids synthesis decreases after laparoscopic sleeve gastrectomy.

Journal: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
PMID: 26948941

Abstract

BACKGROUND: Bariatric surgery is the most effective treatment alternative in morbid obesity. The mechanisms contributing to these benefits remain poorly understood. Bile acids (BAs) are mediators of different regulatory functions in glucose and cholesterol homeostasis and energy expenditure. Recent evidence suggests that BAs are critically important for the beneficial effects of sleeve gastrectomy (SG).

Authors

  • Alex Escalona
    Department of Surgery. Faculty of Medicine, Universidad de los Andes, Santiago, Chile. Electronic address: aescalona@clinicauandes.cl.
  • Rodrigo Muñoz
    Department of Digestive Surgery, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Veronica Irribarra
    Department of Nutrition, Diabetes and Metabolism, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Sandra Solari
    Departamento de Laboratorios Clínicos, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Fidel Allende
    Departamento de Laboratorios Clínicos, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Juan Francisco Miquel
    Department of Gastroenterology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.

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