AIMC Topic: Bile Acids and Salts
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Machine learning-causal inference based on multi-omics data reveals the association of altered gut bacteria and bile acid metabolism with neonatal jaundice.
Gut microbes
Aug 21, 2024
Early identification of neonatal jaundice (NJ) appears to be essential to avoid bilirubin encephalopathy and neurological sequelae. The interaction between gut microbiota and metabolites plays an important role in early life. It is unclear whether th...
Deep learning quantification reveals a fundamental prognostic role for ductular reaction in biliary atresia.
Hepatology communications
Dec 1, 2023
BACKGROUND: We aimed to quantify ductular reaction (DR) in biliary atresia using a neural network in relation to underlying pathophysiology and prognosis.
Deep Learning Algorithm-Based Magnetic Resonance Imaging Feature-Guided Serum Bile Acid Profile and Perinatal Outcomes in Intrahepatic Cholestasis of Pregnancy.
Computational and mathematical methods in medicine
Jun 6, 2022
This study was aimed to explore magnetic resonance imaging (MRI) based on deep learning belief network model in evaluating serum bile acid profile and adverse perinatal outcomes of intrahepatic cholestasis of pregnancy (ICP) patients. Fifty ICP pregn...
[The role of bile acid measurement in the management of intrahepatic cholestasis of pregnancy].
Orvosi hetilap
May 15, 2022
Introduction: Intrahepatic cholestasis of pregnancy complicates 1% of pregnancies. It increases the risk of severe fetal complications significantly, including preterm delivery and stillbirth. Objective: To summarize our experience with serum total b...
Intrahepatic cholestasis of pregnancy: machine-learning algorithm to predict elevated bile acid based on clinical and laboratory data.
Archives of gynecology and obstetrics
Feb 19, 2021
PURPOSE: Applying machine-learning models to clinical and laboratory features of women with intrahepatic cholestasis of pregnancy (ICP) and creating algorithm to identify these patients without bile acid measurements.
Bile acids synthesis decreases after laparoscopic sleeve gastrectomy.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
Dec 2, 2015
BACKGROUND: Bariatric surgery is the most effective treatment alternative in morbid obesity. The mechanisms contributing to these benefits remain poorly understood. Bile acids (BAs) are mediators of different regulatory functions in glucose and chole...
Refining in silico simulation to study digestion parameters affecting the bioaccessibility of lipophilic nutrients and micronutrients.
Food & function
Oct 23, 2014
Despite the considerable number of in vivo and in vitro studies on the digestive fate of lipophilic nutrients, micronutrients, and bioactives, the effects of the structure and composition of foods on the physicochemical mechanisms of luminal digestio...
Dietary Fats
Gastric Juice
Triolein
Humans
Computer Simulation
Animals
Computational Biology
Bile Acids and Salts
Chemical Phenomena
Digestion
Viscosity
Triglycerides
Intestinal Absorption
Lipolysis
Solubility
Vitamin A
Hydrophobic and Hydrophilic Interactions
Expert Systems
Food Analysis
Models, Biological
Caprylates
Improvement of solubility and dissolution of ebastine by fabricating phosphatidylcholine/ bile salt bilosomes.
Pakistan journal of pharmaceutical sciences
Sep 1, 2020
Although ebastine (EBT) can impede histamine-induced skin allergic reaction and persuade long acting selective H1 receptor antagonistic effects but its poor water solubility circumscribed its clinical application. The main objective of this research ...
The Starfish Assassin.
Scientific American
Jan 1, 2016
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