Classification of Three Anesthesia Stages Based on Near-Infrared Spectroscopy Signals.

Journal: IEEE journal of biomedical and health informatics
PMID:

Abstract

Proper monitoring of anesthesia stages can guarantee the safe performance of clinical surgeries. In this study, different anesthesia stages were classified using near-infrared spectroscopy (NIRS) signals with machine learning. The cerebral hemodynamic variables of right proximal oxyhemoglobin (HbO) in maintenance (MNT), emergence (EM) and the consciousness (CON) stage were collected and then the differences between the three stages were compared by phase-amplitude coupling (PAC). Then combined with time-domain including linear (mean, standard deviation, max, min and range), nonlinear (sample entropy) and power in frequency-domain signal features, feature selection was performed and finally classification was performed by support vector machine (SVM) classifier. The results show that the PAC of the NIRS signal was gradually enhanced with the deepening of anesthesia level. A good three-classification accuracy of 69.27% was obtained, which exceeded the result of classification of any single category feature. These results indicate the feasibility of NIRS signals in performing three or even more anesthesia stage classifications, providing insight into the development of new anesthesia monitoring modalities.

Authors

  • Zhian Liu
  • Lichengxi Si
  • Shaoxian Shi
  • Jing Li
    Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
  • Jing Zhu
    College of Environmental Science and Engineering, Beijing Forestry University, Beijing 100083, China.
  • Won Hee Lee
    Department of Software Convergence, Kyung Hee University, Yongin 17104, Korea.
  • Sio-Long Lo
    Faculty of Information Technology, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau, China. luoslresearch@gmail.com.
  • Xiangguo Yan
  • Badong Chen
    Institute of Artificial Intelligence and Robotics, School of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, Shaanxi, 710049, China.
  • Feng Fu
    Department of Mathematics, Dartmouth College, Hanover, NH 03755, USA.
  • Yang Zheng
    Provincial Key Laboratory of Informational Service for Rural Area of Southwestern Hunan, Shaoyang University, Shaoyang, China.
  • Gang Wang
    National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.