An ultrasonography of thyroid nodules dataset with pathological diagnosis annotation for deep learning.

Journal: Scientific data
PMID:

Abstract

Ultrasonography (US) of thyroid nodules is often time consuming and may be inconsistent between observers, with a low positivity rate for malignancy in biopsies. Even after determining the ultrasound Thyroid Imaging Reporting and Data System (TIRADS) stage, Fine needle aspiration biopsy (FNAB) is still required to obtain a definitive diagnosis. Although various deep learning methods were developed in medical field, they tend to be trained using TI-RADS reports as image labels. Here, we present a large US dataset with pathological diagnosis annotation for each case, designed for developing deep learning algorithms to directly infer histological status from thyroid ultrasound images. The dataset was collected from two retrospective cohorts, which consists of 8508 US images from 842 cases. Additionally, we explained three deep learning models used as validation examples using this dataset.

Authors

  • Xiaowen Hou
    Minfound Medical Systems Co. Ltd., 8 Dongze Road, Yuecheng District, Shaoxing, Zhejiang, 312099, China.
  • Menglei Hua
    Department of Biostatistics, School of Public Health, Harbin Medical University, Harbin, 150081, China.
  • Wei Zhang
    The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Jianxin Ji
    Department of Biostatistics, School of Public Health, Harbin Medical University, Harbin 150081, China.
  • Xuan Zhang
  • Huiru Jiang
    Department of Cardiology Renji Hospital, Shanghai Jiao Tong University, Shanghai, 200127, China.
  • Mengyun Li
    The Ohio State University.
  • Xiaoxiao Wu
    Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province 215006, China; Suzhou Medical College of Soochow University, Suzhou, Jiangsu Province 215002, China.
  • Wenwen Zhao
    Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Ningbo, China.
  • Shuxin Sun
    Department of Ultrasonography, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China. m15776606672@163.com.
  • Lei Cao
    State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, Liaoning, People's Republic of China. Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang, Liaoning, People's Republic of China. University of Chinese Academy of Sciences, Beijing, People's Republic of China.
  • Liuying Wang