Machine learning in image-based outcome prediction after radiotherapy: A review.

Journal: Journal of applied clinical medical physics
Published Date:

Abstract

The integration of machine learning (ML) with radiotherapy has emerged as a pivotal innovation in outcome prediction, bringing novel insights amid unique challenges. This review comprehensively examines the current scope of ML applications in various treatment contexts, focusing on treatment outcomes such as patient survival, disease recurrence, and treatment-induced toxicity. It emphasizes the ascending trajectory of research efforts and the prominence of survival analysis as a clinical priority. We analyze the use of several common medical imaging modalities in conjunction with clinical data, highlighting the advantages and complexities inherent in this approach. The research reflects a commitment to advancing patient-centered care, advocating for expanded research on abdominal and pancreatic cancers. While data collection, patient privacy, standardization, and interpretability present significant challenges, leveraging ML in radiotherapy holds remarkable promise for elevating precision medicine and improving patient care outcomes.

Authors

  • Xiaohan Yuan
    Department of Radiology, Changhai Hospital.
  • Chaoqiong Ma
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.
  • Mingzhe Hu
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
  • Richard L J Qiu
    Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, United States of America.
  • Elahheh Salari
    Department of Radiation Oncology, Emory University, Atlanta, Georgia, USA.
  • Reema Martini
    Emory School of Medicine, Emory University, Atlanta, Georgia, USA.
  • Xiaofeng Yang
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.