Predicting Asthma Exacerbations Using Machine Learning Models.

Journal: Advances in therapy
PMID:

Abstract

INTRODUCTION: Although clinical, functional, and biomarker data predict asthma exacerbations, newer approaches providing high accuracy of prognosis are needed for real-world decision-making in asthma. Machine learning (ML) leverages mathematical and statistical methods to detect patterns for future disease events across large datasets from electronic health records (EHR). This study conducted training and fine-tuning of ML algorithms for the real-world prediction of asthma exacerbations in patients with physician-diagnosed asthma.

Authors

  • Gianluca Turcatel
    Digital Health and Innovation, Amgen Inc., Thousand Oaks, CA, USA.
  • Yi Xiao
    Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China.
  • Scott Caveney
    Global Development, Amgen Inc., One Amgen Center Dr, Thousand Oaks, CA, 91320, USA.
  • Gilles Gnacadja
    Digital Health and Innovation, Amgen Inc., Thousand Oaks, CA, USA.
  • Julie Kim
    Department of Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, United States of America.
  • Nestor A Molfino
    Global Development, Amgen Inc., One Amgen Center Dr, Thousand Oaks, CA, 91320, USA. nmolfino@amgen.com.