[Development and validation of a new HPLC method for determination of Lamotrigine and clinical application].
Journal:
La Tunisie medicale
PMID:
26815525
Abstract
BACKGROUND: Lamotrigine is an effective anticonvulsant drug used in the treatment of epilepsy. It has a narrow therapeutic range, a large inter and intra-individual pharmacokinetic variability and some concentration-dependent side effects.