Uncovering key predictive channels and clinical variables in the gamma band auditory steady-state response in early-stage psychosis: a longitudinal study.

Journal: Acta neuropsychiatrica
PMID: 39648748

Abstract

OBJECTIVE: Psychotic disorders are characterised by abnormalities in the synchronisation of neuronal responses. A 40 Hz gamma band deficit during auditory steady-state response (ASSR) measured by electroencephalogram (EEG) is a robust observation in psychosis and is associated with symptoms and functional deficits. However, the majority of ASSR studies focus on specific electrode sites, while whole scalp analysis using all channels, and the association with clinical symptoms, are rare.

Authors

  • Kristina M Holton
    Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, USA.
  • Amy Higgins
    Psychosis Neurobiology Laboratory, McLean Hospital, Belmont, MA, USA.
  • Austin J Brockmeier
  • Mei-Hua Hall
    Psychosis Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Mill St, Belmont, MA, USA. mhall@mclean.harvard.edu.

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