Computed Tomography-Based Radiomics with Machine Learning Outperforms Radiologist Assessment in Estimating Colorectal Liver Metastases Pathologic Response After Chemotherapy.

Journal: Annals of surgical oncology
PMID: 39369120

Abstract

OBJECTIVES: This study was designed to assess computed tomography (CT)-based radiomics of colorectal liver metastases (CRLM), extracted from posttreatment scans in estimating pathologic treatment response to neoadjuvant therapy, and to compare treatment response estimates between CT-based radiomics and radiological response assessment by using RECIST 1.1 and CT morphologic criteria.

Authors

  • Georgios Karagkounis
    Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Natally Horvat
    Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Sofia Danilova
    Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Salini Chhabra
    Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Raja R Narayan
    Department of Surgery, Mass General, Boston MA, United States.
  • Ahmad B Barekzai
    Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Adam Kleshchelski
    Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Chou Joanne
    Department of Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Mithat Gonen
    Department of Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Vinod Balachandran
    Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Kevin C Soares
    Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Alice C Wei
    Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • T Peter Kingham
    Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY. Electronic address: kinghamt@mskcc.org.
  • William R Jarnagin
    Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY.
  • Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Jayasree Chakraborty
    Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Michael I D'Angelica
    Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY.

Keywords

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