Serial change of C1 inhibitor in patients with sepsis--a preliminary report.

Journal: The American journal of emergency medicine
Published Date: Dec 19, 2015

Abstract

OBJECTIVE: C1 inhibitor (C1INH) regulates not only the complement system but also the plasma kallikrein-kinin, fibrinolytic, and coagulation systems. The biologic activities of C1INH can be divided into the regulation of vascular permeability and anti-inflammatory functions. The objective was to clarify the serial change of C1INH in patients with sepsis.

Authors

  • Tomoya Hirose
    Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan. Electronic address: htomoya1979@hp-emerg.med.osaka-u.ac.jp.
  • Hiroshi Ogura
    Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
  • Jinkoo Kang
    Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
  • Youhei Nakamura
    Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
  • Hideo Hosotsubo
    Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
  • Etsuko Kitano
    Department of Medical Technology, Faculty of Health Sciences, Kobe Tokiwa University, Kobe-shi, Hyogo 653-0838, Japan.
  • Michiyo Hatanaka
    Department of Medical Technology, Faculty of Health Sciences, Kobe Tokiwa University, Kobe-shi, Hyogo 653-0838, Japan.
  • Takeshi Shimazu
    Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

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