Sepsis, septic shock, and cardiogenic shock are life-threatening conditions associated with high mortality rates, but differentiating them is complex because they share certain symptoms. Using the Medical Information Mart for Intensive Care (MIMIC)-I...
Patients with intracerebral hemorrhage (ICH) are highly susceptible to sepsis. This study evaluates the efficacy of machine learning (ML) models in predicting sepsis risk in intensive care units (ICUs) patients with ICH. We conducted a retrospective ...
Frontiers in cellular and infection microbiology
40313459
BACKGROUND: Sepsis associated encephalopathy (SAE) is prevalent among elderly patients in the ICU and significantly affects patient prognosis. Due to the symptom similarity with other neurological disorders and the absence of specific biomarkers, ear...
Small Ubiquitin-like MOdifier-mediated modification (SUMOylation) is associated with sepsis; however, its molecular mechanism remains unclear. Herein, hub genes and regulatory mechanisms in sepsis was investigated. The GSE65682 and GSE95233 datasets ...
OBJECTIVE: The aim of this study was to construct interpretable machine learning models to predict the risk of developing delirium in patients with sepsis and to explore the impact of delirium on the 28-day survival rate of patients.
INTRODUCTION: Sepsis is a life-threatening condition characterized by widespread inflammatory response syndrome in the body resulting from infection. Previous studies have demonstrated that some inflammatory factors or nutritional elements contribute...
BACKGROUND: Acute respiratory distress syndrome (ARDS) is a severe complication associated with a high mortality rate in patients with sepsis. Early identification of patients with sepsis at high risk of developing ARDS is crucial for timely interven...
BACKGROUND: Sepsis, a complex inflammatory condition with high mortality rates, lacks effective treatments. This study explores the therapeutic mechanisms of Calculus Bovis in sepsis using network pharmacology and RNA sequencing.
We aimed to develop machine learning(ML) algorithms to evaluate complications of flexible ureteroscopy and laser lithotripsy(fURSL), providing a valid predictive model. 15 ML algorithms were trained on a large number fURSL data from > 6500 patients f...
BMC medical informatics and decision making
40369550
BACKGROUND: Bloodstream Infection (BSI) is a severe systemic infectious disease that can lead to sepsis and Multiple Organ Dysfunction Syndrome (MODS), resulting in high mortality rates and posing a major public health burden globally. Early identifi...