Identification of glucocorticoid-related genes in systemic lupus erythematosus using bioinformatics analysis and machine learning.

Journal: PloS one
PMID:

Abstract

BACKGROUND: Systemic lupus erythematosus (SLE) is a complex autoimmune disease that has significant impacts on patients' quality of life and poses a substantial economic burden on society.

Authors

  • Yinghao Ren
    Department of Dermatology, Xiamen Humanity Hospital Fujian Medical University, Xiamen, Fujian, China.
  • Weiqiang Chen
    Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000, China; Key Laboratory of Basic Research on Heavy Ion Radiation Application in Medicine, Gansu Province, Lanzhou 730000, China; University of Chinese Academy of Sciences, Beijing 100049, China; Putian Lanhai Nuclear Medicine Research Center, Putian 351152, China.
  • Yuhao Lin
    Department of Endocrinology, Xiamen Humanity Hospital Fujian Medical University, Xiamen, Fujian, China.
  • Zeyu Wang
    Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
  • Weiliang Wang
    Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, 430074, China.