AI-based non-invasive imaging technologies for early autism spectrum disorder diagnosis: A short review and future directions.

Journal: Artificial intelligence in medicine
PMID:

Abstract

Autism Spectrum Disorder (ASD) is a neurological condition, with recent statistics from the CDC indicating a rising prevalence of ASD diagnoses among infants and children. This trend emphasizes the critical importance of early detection, as timely diagnosis facilitates early intervention and enhances treatment outcomes. Consequently, there is an increasing urgency for research to develop innovative tools capable of accurately and objectively identifying ASD in its earliest stages. This paper offers a short overview of recent advancements in non-invasive technology for early ASD diagnosis, focusing on an imaging modality, structural MRI technique, which has shown promising results in early ASD diagnosis. This brief review aims to address several key questions: (i) Which imaging radiomics are associated with ASD? (ii) Is the parcellation step of the brain cortex necessary to improve the diagnostic accuracy of ASD? (iii) What databases are available to researchers interested in developing non-invasive technology for ASD? (iv) How can artificial intelligence tools contribute to improving the diagnostic accuracy of ASD? Finally, our review will highlight future trends in ASD diagnostic efforts.

Authors

  • Mostafa Abdelrahim
    Bioengineering Department, University of Louisville, Louisville, KY 40292, USA.
  • Mohamed Khudri
    Bioengineering Department, University of Louisville, Louisville, KY 40292, USA.
  • Ahmed Elnakib
    School of Engineering, Penn State Erie-The Behrend College, Erie, PA 16563, USA.
  • Mohamed Shehata
    Department of Bioengineering, Speed School of Engineering, University of Louisville, Louisville, KY, United States.
  • Kate Weafer
    Neuroscience Program, Departments of Biology and Psychology, Bellarmine University, Louisville, KY, USA.
  • Ashraf Khalil
    3 Electrical and Computer Engineering Department, Abu Dhabi University, Abu Dhabi, United Arab Emirates.
  • Gehad A Saleh
    Diagnostic and Interventional Radiology Department, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.
  • Nihal M Batouty
    Diagnostic and Interventional Radiology Department, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.
  • Mohammed Ghazal
    3 Electrical and Computer Engineering Department, Abu Dhabi University, Abu Dhabi, United Arab Emirates.
  • Sohail Contractor
    Center for Artificial Intelligence in Radiological Sciences (CAIRS), Department of Radiology, University of Louisville, Louisville, KY, USA.
  • Gregory Barnes
    Department of Neurology, Pediatric Research Institute, University of Louisville, Louisville, KY 40202, USA.
  • Ayman El-Baz
    Bioengineering Department, The University of Louisville, Louisville, KY, USA.