Quantitative assessment of the generalizability of a brain tumor Raman spectroscopy machine learning model to various tumor types including astrocytoma and oligodendroglioma.

Journal: Journal of biomedical optics
PMID: 39866856

Abstract

SIGNIFICANCE: Maximal safe resection of brain tumors can be performed by neurosurgeons through the use of accurate and practical guidance tools that provide real-time information during surgery. Current established adjuvant intraoperative technologies include neuronavigation guidance, intraoperative imaging (MRI and ultrasound), and 5-ALA for fluorescence-guided surgery.

Authors

  • Frederic Leblond
    Polytechnique Montreal, Department of Engineering Physics, CP 6079, Succ. Centre-Ville, Montreal, Quebec H3C 3A7, CanadadCentre de Recherche du Centre Hospitalier de l'Université de Montréal, 900 rue Saint-Denis, H2X 0A9 Quebec, Canada.
  • Frédérick Dallaire
    Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
  • Katherine Ember
    Polytechnique Montréal, Department of Engineering Physics, Montreal, Quebec, Canada.
  • Alice Le Moël
    Polytechnique Montréal, Department of Engineering Physics, Montreal, Quebec, Canada.
  • Victor Blanquez-Yeste
    Polytechnique Montréal, Department of Engineering Physics, Montreal, Quebec, Canada.
  • Hugo Tavera
    Polytechnique Montréal, Department of Engineering Physics, Montreal, Quebec, Canada.
  • Guillaume Sheehy
    Department of Engineering Physics, Polytechnique Montréal, Montreal, Quebec, Canada. frederic.leblond@polymtl.ca.
  • Trang Tran
    Department of Engineering Physics, Polytechnique Montréal, Montreal, Quebec, Canada. frederic.leblond@polymtl.ca.
  • Marie-Christine Guiot
    McGill University, Division of Neuropathology, Department of Pathology, 3801 University Street, Montreal, Quebec H3A 2B4, Canada.
  • Alexander G Weil
    Division of Neurosurgery, Saint Justine University Hospital Center, University of Montreal, Montreal, Quebec, Canada.
  • Roy Dudley
    Department of Neurosurgery, McGill University, Montreal, H3A 2B4, Canada.
  • Costas Hadjipanayis
    University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States.
  • Kevin Petrecca
    McGill University, Montreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, 3801 University Street, Montreal, Quebec H3A 2B4, Canada.

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