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Spectrum Analysis, Raman

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Machine learning-assisted surface-enhanced raman spectroscopy for the rapid determination of the glutathione redox ratio.

The Analyst
Rapid and accurate detection of glutathione in its reduced (GSH) and oxidized (GSSG) forms is essential for monitoring oxidative stress in biological systems. Oxidative stress is a key indicator of various diseases, and glutathione plays a vital role...

A machine learning approach fusing multisource spectral data for prediction of floral origins and taste components of Apis cerana honey.

Food research international (Ottawa, Ont.)
This study explores the use of near-infrared (NIR), mid-infrared (MIR), and Raman spectral fusion for the rapid prediction of floral origins and main taste components in Apis cerana (A. cerana) honey. Feature-level fusion with the partial least squar...

Rapid and sensitive detection of pharmaceutical pollutants in aquaculture by aluminum foil substrate based SERS method combined with deep learning algorithm.

Analytica chimica acta
BACKGROUND: Pharmaceutical residual such as antibiotics and disinfectants in aquaculture wastewater have significant potential risks for environment and human health. Surface enhanced Raman spectroscopy (SERS) has been widely used for the detection o...

Rapid pathologic grading-based diagnosis of esophageal squamous cell carcinoma Raman spectroscopy and a deep learning algorithm.

World journal of gastroenterology
BACKGROUND: Esophageal squamous cell carcinoma is a major histological subtype of esophageal cancer. Many molecular genetic changes are associated with its occurrence. Raman spectroscopy has become a new method for the early diagnosis of tumors becau...

Single-Molecule SERS Discrimination of Proline from Hydroxyproline Assisted by a Deep Learning Model.

Nano letters
Discriminating low-abundance hydroxylation is a crucial and unmet need for early disease diagnostics and therapeutic development due to the small hydroxyl group with 17.01 Da. While single-molecule surface-enhanced Raman spectroscopy (SERS) sensors c...

AI-assisted SERS imaging method for label-free and rapid discrimination of clinical lymphoma.

Journal of nanobiotechnology
BACKGROUND: Lymphoma is a malignant tumor of the immune system and its incidence is increasing year after year, causing a major threat to people's health. Conventional diagnosis of lymphoma basically depends on histological images consuming long-time...

Rapid diagnosis of membranous nephropathy based on kidney tissue Raman spectroscopy and deep learning.

Scientific reports
Membranous nephropathy (MN) is one of the most common glomerular diseases. Although the diagnostic method based on serum PLA2R antibodies has gradually been applied in clinical practice, only 52-86% of PLA2R-associated MN patients show positive anti-...

DeepATsers: a deep learning framework for one-pot SERS biosensor to detect SARS-CoV-2 virus.

Scientific reports
The integration of Artificial Intelligence (AI) techniques with medical kits has revolutionized disease diagnosis, enabling rapid and accurate identification of various conditions. We developed a novel deep learning model, namely DeepATsers based on ...

Transfer learning from inorganic materials to ivory detection.

Scientific reports
This paper describes the automatic identification of ivory using Raman spectroscopy data and deep neural network (DNN) models pre-trained on open-source data from inorganic minerals. The proposed approach uses transfer learning (TL) from foundation m...

Classification of disease subtypes in medical spectroscopy for multi-category sample imbalances based on grouping and hierarchical learning.

Lasers in medical science
In the medical domain, the challenges in sample acquisition and collection often result in imbalanced training sets for multi-class models, especially in disease subtype differentiation. We propose a novel method to address multi-class imbalance in s...