Pyrethroid pesticide residues pose a significant global public health challenge, particularly in complex edible fungus matrices where trace, structurally similar pesticides are difficult to distinguish and detect. To address this critical gap, a nove...
Recently, pharmaceutical cocrystal technology has garnered considerable global attention because of its innovativeness and environmental sustainability. This technology effectively enhances the bioavailability of poorly soluble drugs and optimizes th...
Gastric cancer (GC) remains a significant global health challenge with high mortality rates, often due to late-stage diagnosis. We hypothesize that Raman spectroscopy (RS) (a modern minimally invasive technique that uses light to analyze the molecula...
Butyrylcholinesterase (BChE) may serve as a scavenger enzyme protecting against various toxic compounds, but we still don't fully understand how it interacts with fentanyl analogues. We investigated how Despropionyl -methyl fentanyl (DPPM) inhibits e...
As primary carriers of foodborne and zoonotic diseases, spores can pose a serious threat to food microbiology and human disease. Thus, the precise identification of spores is of great significance for ensuring food safety and human health. Herein, ...
The journal of physical chemistry letters
Jan 4, 2026
Fast intraoperative histopathology is critical for optimal surgery in ovarian, endometrial and cervical cancers, yet frozen-section pathology is slow and resource-intensive. We obtained 4750 Raman spectra from 85 human gynecological tissue specimens ...
Bloodstream infections caused by spp. are among the leading hospital-acquired infections, but their diagnosis remains slow and challenging with conventional culture-based methods, which often require days to deliver results. This study aimed to deve...
The escalating global crisis of multidrug-resistant (MDR) bacteria demands innovative strategies that bypass conventional antibiotic limitations. This study introduced a multifunctional Au@CuSe core-shell nanoplatform integrating artificial intellige...
Hair dyeing is a widespread practice with potential forensic value in individual identification, yet most analytical approaches are destructive, time-intensive, or lack sensitivity for trace residues. Surface-enhanced Raman spectroscopy (SERS) offers...
Transient ischemic attack (TIA) serves as a critical early warning sign for ischemic stroke. Its timely identification holds significant clinical value in reducing recurrence risk and improving patient prognosis. However, existing detection methods e...
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