Automated AI-based image analysis for quantification and prediction of interstitial lung disease in systemic sclerosis patients.

Journal: Respiratory research
PMID: 39856708

Abstract

BACKGROUND: Systemic sclerosis (SSc) is a rare connective tissue disease associated with rapidly evolving interstitial lung disease (ILD), driving its mortality. Specific imaging-based biomarkers associated with the evolution of lung disease are needed to help predict and quantify ILD.

Authors

  • Julien Guiot
    Dept of Respiratory Medicine, CHU of Liège, Liège, Belgium.
  • Monique Henket
    Department of Respiratory Medicine, University Hospital of Liège, Liège, Belgium.
  • Fanny Gester
    Department of Respiratory Medicine, University Hospital of Liège, Liège, Belgium.
  • Béatrice André
    Department of Rheumatology, University Hospital of Liège, Liège, Belgium.
  • Benoit Ernst
    Department of Respiratory Medicine, University Hospital of Liège, Liège, Belgium.
  • Anne-Noelle Frix
    Dept of Respiratory Medicine, CHU of Liège, Liège, Belgium.
  • Dirk Smeets
    icometrix NV, Leuven, Belgium.
  • Simon Van Eyndhoven
    icometrix, Leuven, Belgium.
  • Katerina Antoniou
    Laboratory of Cellular and Molecular Pneumonology, School of Medicine, University of Crete, Heraklion, Crete, Greece.
  • Lennart Conemans
    Department of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.
  • Janine Gote-Schniering
    Department of Rheumatology and Immunology, Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
  • Hans Slabbynck
    Department of Pneumology, ZNA Middelheim, Antwerpen, Belgium.
  • Michael Kreuter
    Mainz Center for Pulmonary Medicine, Department of Pneumology, Department of Pulmonary, ZfT, Mainz University Medical Center and Department of Pulmonary, Critical Care and Sleep Medicine, Marienhaus Clinic Mainz, Mainz, Germany.
  • Jacobo Sellarés
    Hospital Clinic de Barcelona-IDIBPAS, Barcelona, Spain.
  • Ioannis Tomos
    Department of Pulmonary Medicine, SOTIRIA Chest Diseases Hospital of Athens, Athens, Greece.
  • Guang Yang
    National Heart and Lung Institute, Imperial College London, London, UK.
  • Clio Ribbens
    Department of Rheumatology, University Hospital of Liège, Liège, Belgium.
  • Renaud Louis
    Dept of Respiratory Medicine, University Hospital, Liege, Belgium.
  • Vincent Cottin
    National Reference Center for Rare Pulmonary Diseases, Louis Pradel Hospital, Hospices Civils de Lyon, Claude Bernard University Lyon 1, UMR 754, Lyon, France.
  • Sara Tomassetti
    Department of Thoracic Diseases, Morgagni-Pierantoni Hospital, Forlì, Italy.
  • Vanessa Smith
    Department of Internal Medicine, Ghent University, Ghent, Belgium.
  • Simon L F Walsh
    Department of Radiology, King's College Hospital Foundation Trust, London, UK. Electronic address: slfwalsh@gmail.com.

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