Diagnosis of lymph node metastasis in oral squamous cell carcinoma by an MRI-based deep learning model.

Journal: Oral oncology
PMID: 39752793

Abstract

BACKGROUND: Cervical lymph node metastasis (LNM) is a well-established poor prognosticator of oral squamous cell carcinoma (OSCC), in which occult metastasis is a subtype that makes prediction challenging. Here, we developed and validated a deep learning (DL) model using magnetic resonance imaging (MRI) for the identification of LNM in OSCC patients.

Authors

  • Le Yang
    Department of Computer Science and Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14214, USA.
  • Sien Zhang
    Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Province Key Laboratory of Stomatology, Guangzhou, Guangdong, China.
  • Jinsong Li
    Department of Spine Surgery, The Third Xiangya Hospital of Central South University, 138 Tongzipo Rd, Changsha, 410013, Hunan, China.
  • Chongjin Feng
    Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
  • Lijun Zhu
    State Key Laboratory of Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Sciences, 100083, Beijing, China.
  • Jingyuan Li
    Zhejiang Province Key Laboratory of Quantum Technology and Device, Institute of Quantitative Biology, Department of Physics, Zhejiang University, Hangzhou 310027, Zhejiang, China.
  • Lisong Lin
    Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
  • Xiaozhi Lv
    Department of Oral and Maxillofacial Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Kai Su
    Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Province Key Laboratory of Stomatology, Guangzhou, Guangdong, China.
  • Xiaomei Lao
    Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Province Key Laboratory of Stomatology, Guangzhou, Guangdong, China.
  • Jufeng Chen
    Department of Oral and Maxillofacial Surgery, Foshan First People's Hospital, Foshan, Guangdong, China.
  • Wei Cao
    Collaborative Innovation Center for Green Chemical Manufacturing and Accurate Detection, Key Laboratory of Interfacial Reaction & Sensing Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, PR China.
  • Siyi Li
    College of Mechanical and Electrical Engineering, Fujian Agriculture and Forestry University, 63 Xiyuangong Road, Fuzhou, 350100, China. Electronic address: 2548303614@qq.com.
  • Hongyi Tang
    Department of Oral and Maxillofacial Surgery, Gaozhou People's Hospital, Gaozhou, Guangdong, China.
  • Xueying Chen
    Department of Oral and Maxillofacial Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
  • Lizhong Liang
  • Wei Shang
    Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  • Zhongyi Cao
    Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Nanchang Medical University, Nanchang, Jiangxi, China.
  • Fangsong Qiu
    Department of Oral and Maxillofacial Surgery, Jiangmen Central Hospital, Jiangmen, Guangdong, China.
  • Jun Li
    Department of Emergency, Zhuhai Integrated Traditional Chinese and Western Medicine Hospital, Zhuhai, 519020, Guangdong Province, China. quanshabai43@163.com.
  • Wenhao Luo
    Shanghai University, Chengzhong Road, 201800 Shanghai, China. Electronic address: luowh1008@163.com.
  • Siyong Gao
    Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Province Key Laboratory of Stomatology, Guangzhou, Guangdong, China.
  • Shuqin Wang
    Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; Department of Oral and Maxillofacial Surgery, Guangdong Provincial People's Hospital & Guangdong Academy of Medical Sciences, Guangzhou, China.
  • Bin Zeng
    Jiangxi Key Laboratory of Bioprocess Engineering, Jiangxi Science and Technology Normal University, Nanchang, 330013 People's Republic of China.
  • Wan Duan
    Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Province Key Laboratory of Stomatology, Guangzhou, Guangdong, China.
  • Tong Ji
    Department of Oral and Maxillofacial and Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology, National Clinical Research Center of Stomatology, Shanghai, China. Electronic address: jitong70@hotmail.com.
  • Guiqing Liao
    Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Province Key Laboratory of Stomatology, Guangzhou, Guangdong, China. Electronic address: liaogq@mail.sysu.edu.cn.
  • Yujie Liang
    NORENDAR International Ltd., Shijiazhuang 050011, Hebei, China.

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