AIMC Topic: Carcinoma, Squamous Cell
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Quantitative image analysis of the extracellular matrix of esophageal squamous cell carcinoma and high grade dysplasia via two-photon microscopy.
Scientific reports
Aug 7, 2025
Squamous cell carcinoma (SCC) and high-grade dysplasia (HGD) are two different pathological entities; however, they sometimes share similarities in histological structure depending on the context. Thus, distinguishing between the two may require care...
Deep learning using nasal endoscopy and T2-weighted MRI for prediction of sinonasal inverted papilloma-associated squamous cell carcinoma: an exploratory study.
European radiology experimental
Jul 21, 2025
BACKGROUND: Detecting malignant transformation of sinonasal inverted papilloma (SIP) into squamous cell carcinoma (SIP-SCC) before surgery is a clinical need. We aimed to explore the value of deep learning (DL) that leverages nasal endoscopy and T2-w...
Assessment of established prognostic factors and artificial intelligence-based evaluation of tumor-infiltrating lymphocytes in oral tongue squamous cell carcinoma.
Oral oncology
Jul 3, 2025
BACKGROUND: Traditional risk assessment for tongue cancer relies on clinicopathological parameters. Although tumor-infiltrating lymphocytes (TILs) are promising prognostic markers, their evaluation lacks standardization. This study aimed to validate ...
Identification of DSC2 as a Key Biomarker for Induction Chemotherapy Sensitivity in Locally Advanced Laryngeal and Hypopharyngeal Squamous Cell Carcinoma.
Journal of chemical information and modeling
Jun 9, 2025
Patients with locally advanced laryngeal and hypopharyngeal squamous cell carcinoma (LA-LHSCC) urgently need precise treatment strategies to improve the prognosis due to severe laryngeal functional impairment following traditional surgery and chemora...
Global burden of non-melanoma skin cancers among older adults: a comprehensive analysis using machine learning approaches.
Scientific reports
May 1, 2025
Non-melanoma skin cancers (NMSCs), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), have shown significant global increases in burden, particularly among older adults, with wide regional, gender, and socio-demographic dispariti...
Diagnostic Adjuncts and Biopsy Techniques for Oral Potentially Malignant Disorders and Oral Cavity Squamous Cell Carcinoma.
Dental clinics of North America
Apr 25, 2025
Diagnostic adjuncts for oral potentially malignant disorders such as leukoplakia or erythroplakia can aid the clinician in triaging abnormal lesions and facilitate both biopsy site selection and surgical management. No adjuncts replace gold standard ...
Intelligent Diagnosis of Cervical Lymph Node Metastasis Using a CNN Model.
Journal of dental research
Apr 24, 2025
Lymph node (LN) metastasis is a prevalent cause of recurrence in oral squamous cell carcinoma (OSCC). However, accurately identifying metastatic LNs (LNs+) remains challenging. This prospective clinical study aims to test the effectiveness of our con...
Personalized therapeutic strategies and prognosis for advanced laryngeal squamous cell carcinoma: Insights from machine learning models.
American journal of otolaryngology
Apr 24, 2025
PURPOSE: Despite the development of diverse treatment options, there has been an increase in mortality rates for laryngeal squamous cell carcinoma (LSCC). Our research employed survival analysis and machine learning (ML) techniques to evaluate the im...
Pathogenomic fingerprinting to identify associations between tumor morphology and epigenetic states.
European journal of cancer (Oxford, England : 1990)
Apr 14, 2025
INTRODUCTION: Measuring the chromatin state of a tumor provides a powerful map of its epigenetic commitments; however, as these are generally bulk measurements, it has not yet been possible to connect changes in chromatin accessibility to the patholo...
Sub-diffuse Reflectance Spectroscopy Combined With Machine Learning Method for Oral Mucosal Disease Identification.
Lasers in surgery and medicine
Apr 8, 2025
OBJECTIVES: Oral squamous cell carcinoma (OSCC) is the sixth-highest incidence of malignant tumors worldwide. However, early diagnosis is complex owing to the impracticality of biopsying every potentially premalignant intraoral lesion. Here, we prese...
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