AIMC Topic: Carcinoma, Squamous Cell
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Identification of DSC2 as a Key Biomarker for Induction Chemotherapy Sensitivity in Locally Advanced Laryngeal and Hypopharyngeal Squamous Cell Carcinoma.
Journal of chemical information and modeling
Jun 9, 2025
Patients with locally advanced laryngeal and hypopharyngeal squamous cell carcinoma (LA-LHSCC) urgently need precise treatment strategies to improve the prognosis due to severe laryngeal functional impairment following traditional surgery and chemora...
Global burden of non-melanoma skin cancers among older adults: a comprehensive analysis using machine learning approaches.
Scientific reports
May 1, 2025
Non-melanoma skin cancers (NMSCs), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), have shown significant global increases in burden, particularly among older adults, with wide regional, gender, and socio-demographic dispariti...
Personalized therapeutic strategies and prognosis for advanced laryngeal squamous cell carcinoma: Insights from machine learning models.
American journal of otolaryngology
Apr 24, 2025
PURPOSE: Despite the development of diverse treatment options, there has been an increase in mortality rates for laryngeal squamous cell carcinoma (LSCC). Our research employed survival analysis and machine learning (ML) techniques to evaluate the im...
Pathogenomic fingerprinting to identify associations between tumor morphology and epigenetic states.
European journal of cancer (Oxford, England : 1990)
Apr 14, 2025
INTRODUCTION: Measuring the chromatin state of a tumor provides a powerful map of its epigenetic commitments; however, as these are generally bulk measurements, it has not yet been possible to connect changes in chromatin accessibility to the patholo...
Sub-diffuse Reflectance Spectroscopy Combined With Machine Learning Method for Oral Mucosal Disease Identification.
Lasers in surgery and medicine
Apr 8, 2025
OBJECTIVES: Oral squamous cell carcinoma (OSCC) is the sixth-highest incidence of malignant tumors worldwide. However, early diagnosis is complex owing to the impracticality of biopsying every potentially premalignant intraoral lesion. Here, we prese...
Metabolomic machine learning-based model predicts efficacy of chemoimmunotherapy for advanced lung squamous cell carcinoma.
Frontiers in immunology
Apr 2, 2025
BACKGROUND: Unlike lung adenocarcinoma, patients with advanced squamous carcinoma exhibit a low proportion of driver gene positivity, with fewer effective treatment strategies available. Chemoimmunotherapy has now become the standard first-line treat...
Deep learning informed multimodal fusion of radiology and pathology to predict outcomes in HPV-associated oropharyngeal squamous cell carcinoma.
EBioMedicine
Mar 22, 2025
BACKGROUND: We aim to predict outcomes of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC), a subtype of head and neck cancer characterized with improved clinical outcome and better response to therapy. Pathology an...
Artificial intelligence to enhance the diagnosis of ocular surface squamous neoplasia.
Scientific reports
Mar 20, 2025
To provide an artificial intelligence (AI) method using in vivo confocal microscopy (IVCM) to differentiate ocular surface squamous neoplasia (OSSN) from other lesions and compare the performance of well-known AI-related solutions. A dataset of 2,774...
Automated Electrical Detection of Proteins for Oral Squamous Cell Carcinoma in an Integrated Microfluidic Chip Using Multi-Frequency Impedance Cytometry and Machine Learning.
Sensors (Basel, Switzerland)
Mar 4, 2025
Proteins can act as suitable biomarkers for the prognosis and diagnosis of certain conditions and can help us gain an understanding of the fundamental processes that occur inside an organism. In this work, we present a fully automated machine learnin...
Machine learning-based classification of spatially resolved diffuse reflectance and autofluorescence spectra acquired on human skin for actinic keratoses and skin carcinoma diagnostics aid.
Journal of biomedical optics
Mar 4, 2025
SIGNIFICANCE: The incidence of keratinocyte carcinomas (KCs) is increasing every year, making the task of developing new methods for KC early diagnosis of utmost medical and economical importance.
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