Intelligent decoding platform for peptide sequences: SERS detection via high affinity self-assembled silver nanoparticles and machine learning analysis.
Journal:
Analytica chimica acta
PMID:
40024661
Abstract
BACKGROUND: Peptides are compounds formed by the dehydration-condensation reaction of two or more amino acids which play an important role in the life functions of the organism. Changes in the structure of amino acids and peptides are vital for elucidating the process of disease development. However, the existing methods make it difficult to accurately recognize slight variations in peptide sequences, which becomes a difficult detection task. Therefore, the necessity of novel, accurate, comprehensive and deep strategies for peptide sequence identification is imperative.