AIMC Topic: Metal Nanoparticles

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Properties of AgNPs stabilized with polyvinylpyrrolidone relevant to antidiabetic agents.

Nanoscale
Type 2 diabetes mellitus (DM2) is a chronic metabolic disease. Silver nanoparticles (AgNPs) show promise in their treatment. This study assessed the potential of AgNPs as DM2 treatment agent using in vitro, in vivo, and machine learning approaches. M...

Integrating AI-assisted SERS Biosensing and Photoactivated Antibacterial Therapy in Au@CuSe for Combating Multidrug-Resistant Bacteria.

Analytical chemistry
The escalating global crisis of multidrug-resistant (MDR) bacteria demands innovative strategies that bypass conventional antibiotic limitations. This study introduced a multifunctional Au@CuSe core-shell nanoplatform integrating artificial intellige...

AI-Assisted Microfluidic Paper-Based Analytical Device with Au-Pt Nanoparticles for Multiplex, Interference-Resistant Quantification of Urinary Biomarkers.

Analytical chemistry
Urinary glucose, creatinine, and uric acid are vital biomarkers for diabetes and kidney disease management. However, multiplex point-of-care detection faces challenges due to insufficient sensitivity in complex urine matrices and signal cross-talk fr...

Flexible Porous ACH/Ag Surface-Enhanced Raman Scattering Platform for Sensitive Detection and Machine-Learning-Assisted Classification of Multiple Pathogenic Bacteria.

Analytical chemistry
Pathogenic bacteria pose serious threats to public health and environmental safety. Conventional colony counting, a standard method for bacterial detection, is time-consuming and unsuitable for rapid on-site detection. In this work, a flexible ACH/Ag...

Dimeric gold nanoparticles enable multiplexed labeling in cryoelectron tomography.

Proceedings of the National Academy of Sciences of the United States of America
Cryoelectron tomography (cryo-ET) enables three-dimensional visualization of molecular structures within tissue and intact cells, providing a powerful tool for studying the spatial organization of biological components at nanometer resolution. Realiz...

Machine learning-based fabrication of phytogenic NiO nanoparticles for anticancer activity in HepG2 Cell Culture.

Journal of materials science. Materials in medicine
Metal oxide nanomaterials play a central role in biomedical applications due to their unique physicochemical properties. In particular, various treatment methods such as drug delivery, hyperthermia therapy, radiation, and chemotherapy are used for th...

AI-Enhanced Rapid SERS Screening of Trace Quinolone Antibiotics across the Source-Pathway-Sink Ecosystem.

Analytical chemistry
The overused quinolone antibiotics in animal husbandry and clinical medicine pose a growing threat for global health as they enter ecosystem via agricultural discharge and medical wastewater. Consequently, risk assessment for environmental and human ...

A machine learning-enhanced gastric cancer diagnostic method based on shell-isolated nanoparticle-enhanced Raman spectroscopy.

Nanoscale
Gastric cancer (GC) remains one of the most prevalent and lethal malignancies worldwide, necessitating the development of efficient, non-invasive methods for early detection. In this study, a serum diagnostic approach based on shell-isolated nanopart...

Machine learning-assisted multicolor identification and quantification of antidepressant drugs by waste-derived fluorescent nanoprobes: Towards green AI-based electronic tongue.

Analytica chimica acta
Recently, the severe side effects related to the widespread consumption of antidepressants (ADs) have alarmingly created a global challenge for clinics and forensic laboratories. This study introduces a machine learning-empowered multicolor fluoresce...

Construction of a Minimal Sensor Array Using Fingerprint Protein Corona on Nanostars for Detecting Protein Isoforms and Disease States.

ACS nano
Signature-based protein detection coupled with machine learning algorithms has revolutionized traditional sensing methods, providing rapid, inexpensive, and selectivity-driven detection without the use of specialized equipment. This strategy leverage...