AIMC Topic: Metal Nanoparticles

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Lateral flow and colorimetric assay for ketamine detection reinforced with deep learning model interfaced with mobile app for smart alert.

Mikrochimica acta
Point-of-care (POC) devices have grown in popularity due to their ease of use, low cost, and speedy on-site diagnostic capabilities. This study focuses on ketamine detection by colorimetric and lateral flow assays (LFA), with aptamer-based LFA emergi...

Structural modification strategies for ferritin nanoparticles and their applications in biomedicine: a narrative review.

Nanoscale
Ferritin is an iron-storage protein that naturally self-assembles into a hollow spherical particle consisting of 24 identical subunits, and it serves a central role in iron metabolism. Ferritin's favorable drug-loading capacity, biocompatibility, int...

Urea-mediated growth engineering of Au@Ag core-shell nanostructures: an enzymatic detection strategy with machine learning-assisted comparative analysis.

Mikrochimica acta
A non-invasive, enzyme-based colorimetric biosensor was developed for urea detection in saliva, utilizing a growth-based method with Au@Ag core-shell nanostructures, including CTAB-coated gold nanoparticles (AuNPs) and CTAB-coated gold nanorods with ...

Overcoming Fluorescence Interference: "Planar Hotspot" Substrates for Vitamin B Detection with SERS.

Analytical chemistry
Surface-enhanced Raman scattering (SERS) has demonstrated remarkable potential for molecular detection due to its specificity. However, detecting fluorescent vitamin B molecules remains challenging due to fluorescence interference and weak Raman cros...

Optical Resolution of the Morphological Change of Single Nanoparticles at Native Conditions: A Nonsuper-Resolution Approach.

ACS sensors
Label-free optical imaging of the morphology of single nanoparticles under native conditions remains a challenging task despite its importance in the synthesis, properties, and applications of nanomaterials. Here, we developed an angular scanning dar...

Fabrication of serum-based SERS-tailored 3D structures for thyroid cancer diagnosis.

Scientific reports
Early detection of thyroid cancer improves patient survival rate from 51.9% to 99.9%. Fine needle aspiration cytology is the primary method for diagnosing thyroid cancer; however, this method is associated with limitations, including diagnostic uncer...

Split DNA Tetrahedron-Mediated Spatiotemporal-Hierarchy CRISPR Cascade Integrated with Au@Pt Nanolabels and Artificial Intelligence for a Cervical Cancer MicroRNA Bioassay.

ACS nano
The screening and monitoring of microRNAs as cancer molecular biomarkers is clinically significant, but traditional methods lack sufficient sensitivity, accuracy, and convenience. The CRISPR-colorimetric lateral flow assay (CLFA) integration offers a...

Exploring the role of density functional theory in the design of gold nanoparticles for targeted drug delivery: a systematic review.

Journal of molecular modeling
CONTEXT: Targeted drug delivery systems leveraging gold nanoparticles (AuNPs) demand precise atomic-level design to overcome current limitations in drug-loading efficiency and controlled release. Unlike previous focused reviews, this systematic analy...

Prediction of Metal Nanoparticle Interactions with Soil Properties: Machine Learning Insights into Soil Health Dynamics.

ACS nano
Metal nanoparticles (MNPs) offer great potential to enable precision and sustainable agriculture. However, a comprehensive understanding of the interactions between multiple MNPs and soil properties, including impacts on overall soil health, remains ...

Deep learning based rapid X-ray fluorescence signal extraction and image reconstruction for preclinical benchtop X-ray fluorescence computed tomography applications.

Scientific reports
Recent research advances have resulted in an experimental benchtop X-ray fluorescence computed tomography (XFCT) system that likely meets the imaging dose/scan time constraints for benchtop XFCT imaging of live mice injected with gold nanoparticles (...