Interpretable Machine Learning to Predict the Malignancy Risk of Follicular Thyroid Neoplasms in Extremely Unbalanced Data: Retrospective Cohort Study and Literature Review.

Journal: JMIR cancer
PMID:

Abstract

BACKGROUND: Diagnosing and managing follicular thyroid neoplasms (FTNs) remains a significant challenge, as the malignancy risk cannot be determined until after diagnostic surgery.

Authors

  • Rui Shan
    Wannan Medical College, Wuhu, Anhui, China.
  • Xin Li
    Veterinary Diagnostic Center, Shanghai Animal Disease Control Center, Shanghai, China.
  • Jing Chen
    Department of Vascular Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
  • Zheng Chen
  • Yuan-Jia Cheng
    Department of Thyroid and Breast Surgery, Peking University First Hospital, Beijing, China.
  • Bo Han
    Faculty of Material Science and Chemistry, China University of Geosciences, Wuhan 430074, PR China.
  • Run-Ze Hu
    Department of Maternal and Child Health, School of Public Health, Peking University, Beijing, China.
  • Jiu-Ping Huang
    Department of Ultrasound, Peking University Third Hospital, Beijing, China.
  • Gui-Lan Kong
    National Institute of Health Data Science, Peking University, Beijing, China.
  • Hui Liu
    Institute of Urology and Nephrology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
  • Fang Mei
    Department of Pathology, Peking University Third Hospital, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
  • Shi-Bing Song
    Department of General Surgery, Peking University Third Hospital, Beijing, China.
  • Bang-Kai Sun
    Information Management and Big Data Center, Peking University Third Hospital, Beijing, China.
  • Hui Tian
    School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
  • Yang Wang
    Department of General Surgery The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming China.
  • Wu-Cai Xiao
    Department of Maternal and Child Health, School of Public Health, Peking University, Beijing, China.
  • Xiang-Yun Yao
    Department of Ultrasound, Peking University Third Hospital, Beijing, China.
  • Jing-Ming Ye
    Department of Thyroid and Breast Surgery, Peking University First Hospital, Beijing, China.
  • Bo Yu
    Department of Cardiology, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China.
  • Chun-Hui Yuan
    Department of General Surgery, Peking University Third Hospital, Beijing, China.
  • Fan Zhang
    Department of Anesthesiology, Bishan Hospital of Chongqing Medical University, Chongqing, China.
  • Zheng Liu
    ICSC World Laboratory, Geneva, Switzerland.