Rapid and sensitive detection of pharmaceutical pollutants in aquaculture by aluminum foil substrate based SERS method combined with deep learning algorithm.

Journal: Analytica chimica acta
PMID:

Abstract

BACKGROUND: Pharmaceutical residual such as antibiotics and disinfectants in aquaculture wastewater have significant potential risks for environment and human health. Surface enhanced Raman spectroscopy (SERS) has been widely used for the detection of pharmaceuticals due to its high sensitivity, low cost, and rapidity. However, it is remain a challenge for high-sensitivity SERS detection and accurate identification of complex pollutants.

Authors

  • Zixi Huang
    Department of Electrical Engineering, Columbia University, New York, New York, United States of America.
  • Yongqian Lei
    Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center, Guangzhou), Guangzhou, 510070, China; Guangdong Provincial Engineering Research Center for Online Monitoring of Water Pollution, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center, Guangzhou), Guangzhou, 510070, China. Electronic address: yqlei@fenxi.com.cn.
  • Weixin Liang
    Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center, Guangzhou), Guangzhou, 510070, China; Guangdong Provincial Engineering Research Center for Online Monitoring of Water Pollution, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center, Guangzhou), Guangzhou, 510070, China.
  • Yili Cai
    Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center, Guangzhou), Guangzhou, 510070, China; Guangdong Provincial Engineering Research Center for Online Monitoring of Water Pollution, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center, Guangzhou), Guangzhou, 510070, China.
  • Pengran Guo
    Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center, Guangzhou), Guangzhou, 510070, China; Guangdong Provincial Engineering Research Center for Online Monitoring of Water Pollution, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center, Guangzhou), Guangzhou, 510070, China. Electronic address: prguo@fenxi.com.cn.
  • Jian Sun
    Department Of Computer Science, University of Denver, 2155 E Wesley Ave, Denver, Colorado, 80210, United States of America.