A deep learning model for classification of chondroid tumors on CT images.

Journal: BMC cancer
PMID:

Abstract

BACKGROUND: Differentiating chondroid tumors is crucial for proper patient management. This study aimed to develop a deep learning model (DLM) for classifying enchondromas, atypical cartilaginous tumors (ACT), and high-grade chondrosarcomas using CT images.

Authors

  • Felix G Gassert
    Department of Diagnostic and Interventional Radiology, School of Medicine and Klinikum rechts der Isar, Technical University of Munich, 81675, Munich, Germany.
  • Daniel Lang
    Institute of Radiation Medicine, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
  • Nina Hesse
    Department of Radiology, LMU University Hospital, LMU Munich, Marchioninistraße 13, 80337, Munich, Germany.
  • Hans Roland Dürr
    Orthopaedic Oncology, Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), LMU Klinikum, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
  • Alexander Klein
    Orthopaedic Oncology, Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), LMU Klinikum, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
  • Luca Kohll
    Department of Radiology, Klinikum Rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany.
  • Florian Hinterwimmer
    Department of Orthopaedics and Sports Orthopaedics, Klinikum Rechts der Isar, Technical University Munich, Ismaningerstr. 22, 81675, Munich, Germany. florian.hinterwimmer@tum.de.
  • Johanna Luitjens
    Department of Radiology, Klinikum Großhadern, Ludwig-Maximilians-Universität, Marchioninistraße 15, 81377, Munich, Germany.
  • Stefan Weissinger
    Department of Radiology, LMU University Hospital, LMU Munich, Marchioninistraße 13, 80337, Munich, Germany.
  • Jan C Peeken
    Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich (TUM), Ismaninger Straße 22, 81675 Munich, Germany; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Munich, Germany.
  • Carolin Mogler
    From the Department of Radiology (C.E.v.S., V.S.S., Y.L., F.G.G., S.C.F., F.T.G., M.R.M., K.W., A.S.G.), Department for Orthopedics and Orthopedic Sports Medicine (N.J.W., C.K., R.v.E., R.B.), and Institute of Pathology (C.M.), Klinikum Rechts der Isar, Technische Universität München, Ismaninger Str 22, 81675 Munich, Germany; and the Department of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, Freiburg, Germany (M.J., P.M.J., M.F.R.).
  • Carolin Knebel
    From the Department of Radiology (C.E.v.S., V.S.S., Y.L., F.G.G., S.C.F., F.T.G., M.R.M., K.W., A.S.G.), Department for Orthopedics and Orthopedic Sports Medicine (N.J.W., C.K., R.v.E., R.B.), and Institute of Pathology (C.M.), Klinikum Rechts der Isar, Technische Universität München, Ismaninger Str 22, 81675 Munich, Germany; and the Department of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, Freiburg, Germany (M.J., P.M.J., M.F.R.).
  • Stefan Bartzsch
    Institute of Radiation Medicine, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
  • Florian T Gassert
    Department of Diagnostic and Interventional Radiology, School of Medicine and Klinikum rechts der Isar, Technical University of Munich, 81675, Munich, Germany.
  • Alexandra S Gersing
    From the Department of Radiology (C.E.v.S., V.S.S., Y.L., F.G.G., S.C.F., F.T.G., M.R.M., K.W., A.S.G.), Department for Orthopedics and Orthopedic Sports Medicine (N.J.W., C.K., R.v.E., R.B.), and Institute of Pathology (C.M.), Klinikum Rechts der Isar, Technische Universität München, Ismaninger Str 22, 81675 Munich, Germany; and the Department of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, Freiburg, Germany (M.J., P.M.J., M.F.R.).